Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.44 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21229056 | 0.83 | NAMPT (0.38) | HDAC6SMN1; SMN2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL20659199 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5653620 | 0.81 | SMN1; SMN2 (0.53) | HDAC6SMN1; SMN2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL25282343 | 0.80 | HDAC6 (0.42) | FPR2FPR3HDAC6CYP1A2CYP2C19 | |
| SCHEMBL21229129 | 0.78 | NAMPT (0.44) | HDAC6HDAC1HDAC2 | |
| SCHEMBL18209793 | 0.76 | L3MBTL1 (0.41) | FPR2FPR3HTT | |
| SCHEMBL21229124 | 0.75 | HCAR2 (0.40) | FPR2HDAC6SMN1; SMN2HCAR2HPGD | |
| SCHEMBL21229053 | 0.75 | HDAC1 (0.51) | HDAC6SMN1; SMN2CYP1A2HDAC1HDAC2 | |
| SCHEMBL27719736 | 0.75 | SMN1; SMN2 (0.38) | FPR2SMN1; SMN2TSHRCCNE1CDK2 | |
| Bicarbonate SCHEMBL27848216 | 0.73 | CCNE1 (0.45) | SMN1; SMN2MAPK1HDAC1HDAC2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107580595-B | Heterocyclic compounds and their use in the prevention or treatment of bacterial infections | 拜欧蒂姆公司 | 2020-09-18 | — | — | CN | disclosed |
| EP-2427191-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010129497-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-11 | — | — | WO | disclosed |
| EP-1446403-B1 | ARYL SUBSTITUTED OXAZOLIDINONES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2006-04-12 | — | — | EP | disclosed |
| US-20050043374-A1 | Aryl substituted oxazolidinones with antibacterial activity | ASTRAZENECA AB (SE) | 2005-02-24 | — | — | US | disclosed |
| EP-1446403-A1 | ARYL SUBSTITUTED OXAZOLIDINONES WITH ANTIBACTERIAL ACTIVITY | AstraZeneca AB (SE) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003035648-A1 | ARYL SUBSTITUTED OXAZOLIDINONES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2003-05-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043374-A1 | Aryl substituted oxazolidinones with antibacterial activity | HRH2, HDHD5, HRH1 | FPR2 671/4885FPR3 1216/4885HDAC6 485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.