Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 5/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21229056 | 0.83 | NAMPT (0.38) | SMN1; SMN2TSHRHDAC6CYP1A2CYP2D6 | |
| SCHEMBL5684644 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRPOLBALDH1A1MAPT | |
| SCHEMBL290401 | 0.81 | FPR2 (0.44) | SMN1; SMN2TSHRHTTF2HDAC6 | |
| SCHEMBL20659199 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1MAPTRECQLL3MBTL1 | |
| SCHEMBL21229048 | 0.79 | HDAC1 (0.49) | HDAC6 | |
| SCHEMBL6865101 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2TSHRPOLBALDH1A1MAPT | |
| SCHEMBL3255716 | 0.77 | SMN1; SMN2 (0.60) | SMN1; SMN2TSHRPOLBALDH1A1MAPT | |
| SCHEMBL18381560 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRPOLBL3MBTL1KDM4E | |
| Bromide SCHEMBL5048845 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2TSHRPOLBALDH1A1MAPT | |
| SCHEMBL21229053 | 0.75 | HDAC1 (0.51) | SMN1; SMN2ALDH1A1MAPTHDAC6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105908-A1 | Thiazolimine compound and oxazolimine compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
| EP-1640369-A1 | THIAZOLIMINE COMPOUND AND OXAZOLIMINE COMPOUND | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105908-A1 | Thiazolimine compound and oxazolimine compound | CMA1, TH, NPR3 | SMN1; SMN2 3302/4885TSHR 724/4885POLB 3772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.