SCHEMBL29040286

SCHEMBL29040286

O=C(O)c1cnc2c(c1)C(=O)c1cc(C(=O)O)cnc1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 4/20 0.46
HCAR2 Q8TDS4 4/20 0.44
MGAM O43451 1/20 0.43
P4HA1 P13674 2/20 0.42
P4HTM Q9NXG6 2/20 0.42
MIF P14174 1/20 0.41
ALDH1A1 P00352 4/20 0.41
MEN1 O00255 2/20 0.41
POLB P06746 2/20 0.41
KMT2A Q03164 2/20 0.41
HPGD P15428 2/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
APEX1 P27695 1/20 0.41
MAPK1 P28482 1/20 0.41
RECQL P46063 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PTPRC P08575 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7826546 0.79 S100A4 (0.40) TTRHCAR2MGAMP4HA1P4HTM
SCHEMBL2805204 0.77 MGAM (0.42) TTRHCAR2MGAMP4HA1P4HTM
SCHEMBL4678205 0.73 AKT1 (0.54) MGAMP4HA1P4HTMALDH1A1HPGD
SCHEMBL16602016 0.71 MAP4K4 (0.56) MIFMAPK1
SCHEMBL3189213 0.70 KDM4C (0.57) MGAMP4HA1P4HTMKMT2AL3MBTL1
SCHEMBL31058237 0.68 PSMD14 (0.64) HCAR2MGAMP4HA1P4HTMMIF
SCHEMBL1087851 0.68 PSMD14 (0.64) HCAR2MGAMP4HA1P4HTMMIF
SCHEMBL71021 0.67 TTR (0.88) TTRALDH1A1MEN1POLBKMT2A
SCHEMBL600296 0.67 TTR (0.80) TTRALDH1A1MEN1POLBKMT2A
SCHEMBL598301 0.67 TTR (0.88) TTRALDH1A1MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116440954-B Palladium-supported zirconium-based metal organic framework material and preparation method and application thereof 华南理工大学 2024-10-01 CN claimed
CN-117304089-A Application of nitrogen-containing heterofluorenone ligand UiO-67-based palladium catalyst in alkyne conversion 华南理工大学 2023-12-29 CN claimed
CN-116440954-A Palladium-supported zirconium-based metal organic framework material and preparation method and application thereof 华南理工大学 2023-07-18 CN claimed
CN-116440954-B Palladium-supported zirconium-based metal organic framework material and preparation method and application thereof 华南理工大学 2024-10-01 CN disclosed
CN-116440954-B Palladium-supported zirconium-based metal organic framework material and preparation method and application thereof 华南理工大学 2024-10-01 CN disclosed
CN-117304089-A Application of nitrogen-containing heterofluorenone ligand UiO-67-based palladium catalyst in alkyne conversion 华南理工大学 2023-12-29 CN disclosed
CN-117304089-A Application of nitrogen-containing heterofluorenone ligand UiO-67-based palladium catalyst in alkyne conversion 华南理工大学 2023-12-29 CN disclosed
CN-116440954-A Palladium-supported zirconium-based metal organic framework material and preparation method and application thereof 华南理工大学 2023-07-18 CN disclosed
CN-116440954-A Palladium-supported zirconium-based metal organic framework material and preparation method and application thereof 华南理工大学 2023-07-18 CN disclosed