Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 7/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23166438 | 0.77 | HDAC1 (0.51) | HDAC1HDAC6HDAC2HDAC3 | |
| SCHEMBL20116736 | 0.73 | GAA (0.44) | LMNATSHRTP53MAPK1 | |
| SCHEMBL27371818 | 0.73 | TSHR (0.53) | LMNATSHRMAPK1 | |
| SCHEMBL188631 | 0.73 | SMN1; SMN2 (0.41) | TSHR | |
| SCHEMBL29040358 | 0.72 | TRPC6 (0.46) | HDAC1HDAC6HDAC8SMPD1HDAC2 | |
| SCHEMBL34470376 | 0.71 | MAPT (0.47) | LMNAMAPK1 | |
| SCHEMBL6439785 | 0.71 | CYP2C9 (0.51) | LMNATSHRMAPK1 | |
| SCHEMBL10084733 | 0.71 | CRHR1 (0.40) | LMNATSHRMAPK1 | |
| SCHEMBL16532810 | 0.71 | MAPT (0.41) | LMNATSHRMAPK1 | |
| SCHEMBL9830283 | 0.70 | CTNNB1 (0.47) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |