Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.48 |
| ▸ | NPC1 | O15118 | 8/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570816 | 0.79 | CLK4 (0.48) | SMN1; SMN2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL5551741 | 0.77 | DYRK1A (0.56) | SMN1; SMN2NPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL28752915 | 0.76 | MAPT (0.44) | SMN1; SMN2KDM4EHSD17B10TSHRMAPT | |
| SCHEMBL15553105 | 0.75 | CYP1A1 (0.42) | SMN1; SMN2NPC1RAB9AKDM4ETSHR | |
| SCHEMBL27608325 | 0.74 | CA1 (0.37) | SMN1; SMN2NPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL7616076 | 0.73 | ALDH1A1 (0.58) | PDE4ASMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL27589989 | 0.72 | ALDH1A1 (0.48) | SMN1; SMN2NPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL8840880 | 0.72 | PDE4A (0.67) | PDE4ASMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL2207084 | 0.72 | NPC1 (0.42) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL28713706 | 0.71 | CHRNB2 (0.38) | SMN1; SMN2NPC1RAB9AHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |