SCHEMBL29040488

SCHEMBL29040488

FC(F)(F)c1ccc(-n2c3ccccc3c3cc(Br)ccc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
KIF11 P52732 1/20 0.44
PPARG P37231 5/20 0.43
PPARA Q07869 3/20 0.43
TRPV1 Q8NER1 1/20 0.41
TEAD1 P28347 1/20 0.39
TEAD4 Q15561 1/20 0.39
TEAD2 Q15562 1/20 0.39
TEAD3 Q99594 1/20 0.39
TSPO P30536 2/20 0.39
MPI P34949 1/20 0.38
PHOSPHO1 Q8TCT1 1/20 0.38
CYP19A1 P11511 1/20 0.38
MEN1 O00255 1/20 0.37
RAD52 P43351 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30041037 1.00 L3MBTL1 (0.44) L3MBTL1KDM4EATMKIF11PPARG
SCHEMBL28478118 0.91 KIF11 (0.48) L3MBTL1KDM4EATMKIF11PPARG
SCHEMBL17402749 0.88 TEAD1 (0.40) KDM4EKIF11PPARGPPARATRPV1
SCHEMBL45634 0.88 L3MBTL1 (0.50) L3MBTL1KDM4EATMKIF11PPARG
SCHEMBL30481730 0.87 KDM4E (0.46) L3MBTL1KDM4EATMKIF11PPARG
SCHEMBL19768817 0.87 KDM4E (0.46) L3MBTL1KDM4EATMKIF11PPARG
SCHEMBL782608 0.86 L3MBTL1 (0.55) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL29842645 0.86 L3MBTL1 (0.55) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL859629 0.86 L3MBTL1 (0.59) L3MBTL1KDM4EATMKIF11PPARG
SCHEMBL30039561 0.86 L3MBTL1 (0.59) L3MBTL1KDM4EATMKIF11PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115260163-A Imidazole type fluorescent molecule containing carbazole structure, preparation method thereof and application of imidazole type fluorescent molecule as fluorescent probe 江西师范大学 2022-11-01 CN claimed
CN-115260163-B Imidazole type fluorescent molecule containing carbazole structure, preparation method thereof and application of imidazole type fluorescent molecule as fluorescent probe 江西师范大学 2023-07-04 CN disclosed
CN-115260163-A Imidazole type fluorescent molecule containing carbazole structure, preparation method thereof and application of imidazole type fluorescent molecule as fluorescent probe 江西师范大学 2022-11-01 CN disclosed