Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16671758 | 0.83 | HPGD (0.49) | PTPN1HPGDRAB9ATSHRMMP9 | |
| SCHEMBL6450022 | 0.83 | HPGD (0.49) | PTPN1HPGDRAB9ATSHRMMP9 | |
| SCHEMBL29679416 | 0.83 | HPGD (0.49) | PTPN1HPGDRAB9ATSHRMMP9 | |
| SCHEMBL16682036 | 0.82 | MAPT (0.49) | HPGDACERAB9AMMP9PLAUR | |
| SCHEMBL28838109 | 0.81 | SRR (0.46) | HPGDACELMNAALDH1A1 | |
| SCHEMBL16670679 | 0.79 | HPGD (0.47) | HPGDACERAB9AMMP9PLAUR | |
| SCHEMBL28119602 | 0.78 | PPARG (0.53) | ALDH1A1ATM | |
| SCHEMBL28711821 | 0.78 | PPARG (0.53) | ALDH1A1ATM | |
| SCHEMBL16682076 | 0.77 | MMP9 (0.46) | HPGDRAB9AMMP9PLAURNPC1 | |
| SCHEMBL30595262 | 0.77 | HPGD (0.45) | HPGDACERAB9AMMP9PLAUR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507329-A | Novel small molecule compounds for controlling endosomal Toll-like receptor and therapeutic agent for autoimmune disease using the same | S和K 疗法公司 | 2023-07-28 | — | — | CN | disclosed |