Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 9/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29040828 | 0.94 | AKR1C3 (0.50) | AKR1C3AKR1C1NAMPTDRD2DRD3 | |
| SCHEMBL29040775 | 0.91 | AKR1C3 (0.52) | AKR1C3AKR1C1NAMPTDRD2DRD3 | |
| SCHEMBL28369820 | 0.85 | AKR1C3 (0.52) | AKR1C3AKR1C1NAMPTDRD2DRD3 | |
| SCHEMBL566589 | 0.85 | NAMPT (0.54) | AKR1C3AKR1C1NAMPTUSP30 | |
| SCHEMBL20720388 | 0.82 | AKR1C3 (0.48) | AKR1C3AKR1C1NAMPTDRD2DRD3 | |
| SCHEMBL2995065 | 0.81 | ESR2 (0.59) | AKR1C3AKR1C1NAMPTDRD2DRD3 | |
| SCHEMBL17797626 | 0.78 | BRD4 (0.49) | NAMPTHDAC6HDAC8 | |
| SCHEMBL1263462 | 0.78 | ABHD6 (0.50) | AKR1C3NAMPTHDAC6HDAC8 | |
| SCHEMBL21762279 | 0.76 | DRD2 (0.56) | AKR1C3AKR1C1DRD2DRD3 | |
| SCHEMBL24265587 | 0.76 | NR1H2 (0.58) | AKR1C3NAMPTDRD2DRD3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507326-A | Compounds as GLP-1R agonists | 拓臻制药公司 | 2023-07-28 | — | — | CN | disclosed |