Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.45 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25121126 | 0.84 | DRD2 (0.42) | DRD2TBXA2RACSS2MAPTTP53 | |
| SCHEMBL20280108 | 0.80 | TLR7 (0.48) | DRD2TBXA2RACSS2ALDH1A1TP53 | |
| SCHEMBL29559474 | 0.80 | TLR7 (0.48) | DRD2TBXA2RACSS2ALDH1A1TP53 | |
| SCHEMBL24265281 | 0.80 | ACSS2 (0.49) | DRD2TBXA2RACSS2ALDH1A1KDM4E | |
| SCHEMBL25121147 | 0.80 | DRD2 (0.42) | DRD2TBXA2RACSS2MAPTTP53 | |
| Hydrochloric Acid SCHEMBL20266404 | 0.79 | TLR7 (0.47) | DRD2TBXA2RACSS2ALDH1A1TP53 | |
| SCHEMBL22992635 | 0.79 | DRD2 (0.45) | DRD2TBXA2RACSS2MEN1KMT2A | |
| SCHEMBL25121165 | 0.79 | DRD2 (0.41) | DRD2TBXA2RACSS2ALDH1A1MAPT | |
| SCHEMBL31529412 | 0.78 | GLP1R (0.44) | DRD2TBXA2RACSS2ALDH1A1MAPT | |
| SCHEMBL31529396 | 0.78 | DRD2 (0.45) | DRD2TBXA2RACSS2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507326-A | Compounds as GLP-1R agonists | 拓臻制药公司 | 2023-07-28 | — | — | CN | disclosed |