Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.42 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30269337 | 0.89 | GLP1R (0.39) | GLP1RDRD2TBXA2RACSS2KDM4E | |
| SCHEMBL31529391 | 0.82 | DRD2 (0.42) | DRD2TBXA2RACSS2KDM4EMAPT | |
| SCHEMBL31529396 | 0.82 | DRD2 (0.45) | GLP1RDRD2TBXA2RACSS2KDM4E | |
| SCHEMBL30269261 | 0.80 | ALOX5AP (0.44) | DRD2TBXA2RACSS2KDM4E | |
| SCHEMBL29491182 | 0.79 | ALDH1A1 (0.44) | GLP1RACSS2ALDH1A1MEN1MAPT | |
| SCHEMBL20288032 | 0.79 | ALDH1A1 (0.44) | GLP1RACSS2ALDH1A1MEN1MAPT | |
| SCHEMBL29945929 | 0.79 | ALDH1A1 (0.44) | GLP1RACSS2ALDH1A1MEN1MAPT | |
| SCHEMBL20279928 | 0.79 | ALDH1A1 (0.44) | GLP1RACSS2ALDH1A1MEN1MAPT | |
| SCHEMBL30513859 | 0.79 | ALDH1A1 (0.44) | GLP1RACSS2ALDH1A1MEN1MAPT | |
| SCHEMBL27111192 | 0.79 | ALDH1A1 (0.44) | GLP1RACSS2ALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250115612-A1 | CERTAIN 2,5-DIAZABICYCLO[4.2.0]OCTANES AND OCTAHYDROFURO[3,4-B]PYRAZINES AS GLP-1 RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2025-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250115612-A1 | CERTAIN 2,5-DIAZABICYCLO[4.2.0]OCTANES AND OCTAHYDROFURO[3,4-B]PYRAZINES AS GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, GPR119 | GLP1R 1/4885DRD2 1199/4885TBXA2R 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.