Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10720609 | 0.78 | SMN1; SMN2 (0.36) | TSHR | |
| SCHEMBL30540966 | 0.69 | MMP2 (0.43) | TSHR | |
| SCHEMBL14135569 | 0.67 | — | — | |
| SCHEMBL2927608 | 0.67 | — | — | |
| Dimethylamine SCHEMBL6144099 | 0.67 | TSHR (0.34) | TSHR | |
| SCHEMBL18473836 | 0.66 | — | — | |
| SCHEMBL553910 | 0.66 | — | — | |
| SCHEMBL2552780 | 0.62 | TSHR (0.40) | TSHR | |
| SCHEMBL1924525 | 0.62 | LMNA (0.44) | TSHR | |
| SCHEMBL19358122 | 0.61 | SLC1A3 (0.37) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8497106-B2 | Immobilisation of biological molecules | THE UNIVERSITY OF NEWCASTLE (GB) | 2013-07-30 | — | — | US | disclosed |
| US-20100285561-A1 | IMMOBILISATION OF BIOLOGICAL MOLECULES | THE UNIVERSITY OF NEWCASTLE (UK) | 2010-11-11 | — | — | US | disclosed |
| EP-1899730-A2 | IMMOBILISATION OF BIOLOGICAL MOLECULES | University of Newcastle upon Tyne (GB) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007007052-A2 | IMMOBILISATION OF BIOLOGICAL MOLECULES | THE UNIVERSITY OF NEWCASTLE (GB) | 2007-01-18 | — | — | WO | disclosed |