Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2552780 | 0.78 | TSHR (0.40) | MMP2MMP9MMP13SMN1; SMN2TSHR | |
| SCHEMBL10720609 | 0.76 | SMN1; SMN2 (0.36) | MMP2MMP9MMP13SMN1; SMN2TSHR | |
| SCHEMBL1924525 | 0.74 | LMNA (0.44) | TSHRALDH1A1LMNA | |
| SCHEMBL422851 | 0.74 | SMN1; SMN2 (0.53) | MMP2MMP9MMP13SMN1; SMN2TSHR | |
| SCHEMBL27438392 | 0.73 | SMN1; SMN2 (0.37) | MMP2MMP9MMP13SMN1; SMN2TSHR | |
| SCHEMBL28273633 | 0.73 | SMN1; SMN2 (0.33) | SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL9432505 | 0.72 | TSHR (0.34) | SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL3288838 | 0.72 | MEN1 (0.36) | SMN1; SMN2TSHRKMT2AMEN1HPGD | |
| SCHEMBL4813495 | 0.71 | ALDH1A1 (0.40) | TSHRALDH1A1HCAR2HPGDLMNA | |
| SCHEMBL5962166 | 0.70 | ALDH1A1 (0.47) | TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265041-A1 | CURCUMIN ANALOGUES AS ZINC CHELATORS AND TEHIR USES | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265041-A1 | CURCUMIN ANALOGUES AS ZINC CHELATORS AND TEHIR USES | NFRKB, NFKBIA, NFKB1 | MMP2 32/4885MMP9 17/4885MMP13 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.