Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 6/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2904411 | 0.87 | CHRM3 (0.44) | GNAI3GNAO1GNAI1EPHX1CHRM3 | |
| SCHEMBL9544590 | 0.86 | GNAI3 (0.60) | GNAI3GNAO1GNAI1EPHX1GAA | |
| SCHEMBL29991483 | 0.84 | GNAI3 (0.57) | GNAI3GNAO1GNAI1EPHX1GAA | |
| SCHEMBL4484094 | 0.83 | GAA (0.58) | GNAI3GNAO1GNAI1EPHX1GAA | |
| SCHEMBL8487311 | 0.79 | ACHE (0.57) | GNAI3GNAO1GNAI1EPHX1GAA | |
| SCHEMBL8484303 | 0.79 | TDP1 (0.46) | TDP1EPHX1CHRM3GAAACHE | |
| SCHEMBL29990844 | 0.79 | EPHX1 (0.50) | GNAI3GNAO1GNAI1EPHX1CHRM3 | |
| SCHEMBL29372143 | 0.77 | EPHX1 (0.61) | TDP1EPHX1GAATPSAB1TPSD1 | |
| SCHEMBL10879403 | 0.76 | EPHX1 (0.65) | EPHX1GAAEPHX2TPSAB1TPSD1 | |
| SCHEMBL29991599 | 0.76 | MEN1 (0.46) | TDP1GNAI3GNAO1GNAI1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952506-A | Process for the synthesis of 4- 6- (hexylcarbamoyloxy) hexylcarbamoyloxy!-piperidine-1-carboxylic acid 4-phenoxyphenyl ester | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-09-14 | — | — | US | claimed |
| WO-1998047870-A1 | PROCESS FOR THE SYNTHESIS OF 4-[6-(HEXYLCARBAMOYLOXY) HEXYLCARBAMOYLOXY]-PIPERIDINE-1- CARBOXYLIC ACID 4-PHENOXYPHENYL ESTER | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-10-29 | — | — | WO | claimed |