Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.38 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4484094 | 0.90 | GAA (0.58) | EPHX1BCHEGAAGNAI3GNAO1 | |
| SCHEMBL29991483 | 0.89 | GNAI3 (0.57) | EPHX1BCHEGAAGNAI3GNAO1 | |
| SCHEMBL9544590 | 0.87 | GNAI3 (0.60) | EPHX1BCHEGAAGNAI3GNAO1 | |
| SCHEMBL104271 | 0.87 | EPHX1 (0.58) | EPHX1BCHEGAAKCNA3MEN1 | |
| SCHEMBL2897100 | 0.86 | EPHX1 (0.68) | EPHX1BCHEGAAGNAI3GNAO1 | |
| SCHEMBL2904411 | 0.84 | CHRM3 (0.44) | EPHX1BCHEGAAGNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL2897098 | 0.84 | EPHX1 (0.66) | EPHX1BCHEGAAGNAI3GNAO1 | |
| SCHEMBL23200480 | 0.84 | EPHX1 (0.70) | EPHX1BCHEGAAKCNA3MEN1 | |
| SCHEMBL20928290 | 0.84 | EPHX1 (0.65) | EPHX1BCHEGAAKCNA3MEN1 | |
| SCHEMBL29991599 | 0.83 | MEN1 (0.46) | EPHX1GAAGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334307-A1 | CDK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022236058-A1 | CDK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |