Acetone

Acetone

SCHEMBL29044283

CC(C)=O.CCCN[Si](C)(C)C

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 1/20 0.37
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
MMP9 P14780 1/20 0.34
EPHX1 P07099 4/20 0.33
POLB P06746 1/20 0.33
CTSD P07339 1/20 0.33
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 1/20 0.32
MCL1 Q07820 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
LMNA P02545 2/20 0.32
KMT2A Q03164 1/20 0.32
TP53 P04637 2/20 0.31
ADH1B P00325 1/20 0.31
ADH1A P07327 1/20 0.31
ADH7 P40394 1/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL29029493 0.87 CTSD (0.37) PAOXMMP1MMP2MMP3MMP9
SCHEMBL896775 0.86
Dimethylamine SCHEMBL28352145 0.80
SCHEMBL28797723 0.74 PAOX (0.37) PAOXMMP1MMP2MMP3MMP9
Acetone SCHEMBL2672348 0.71 PAOX (0.61) PAOXMMP1MMP2MMP3MMP9
Acetone SCHEMBL7081095 0.69
SCHEMBL21859090 0.69
Acetone SCHEMBL4367700 0.69 PAOX (0.58) PAOXMMP1MMP2MMP3MMP9
SCHEMBL5696489 0.69
SCHEMBL28797719 0.69 PAOX (0.38) PAOXMMP1MMP2MMP3MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112678833-B Nano silicon dioxide modified squalene organic silicon particles and preparation and use methods thereof 广西中烟工业有限责任公司 2023-08-04 CN claimed
CN-112678833-B Nano silicon dioxide modified squalene organic silicon particles and preparation and use methods thereof 广西中烟工业有限责任公司 2023-08-04 CN disclosed