Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 6/20 | 0.54 |
| ▸ | APP | P05067 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727285 | 0.88 | NPC1 (0.49) | ALDH1A3APPNPC1RAB9AALDH1A1 | |
| SCHEMBL1727131 | 0.85 | APP (0.59) | APP | |
| SCHEMBL2904661 | 0.85 | ALDH1A3 (0.60) | ALDH1A3APPNPC1RAB9AALDH1A1 | |
| SCHEMBL1726214 | 0.84 | RAB9A (0.56) | ALDH1A3APPNPC1RAB9AALDH1A1 | |
| SCHEMBL15940370 | 0.83 | HRH3 (0.43) | ALDH1A3APPNPC1RAB9AALDH1A1 | |
| SCHEMBL2435107 | 0.83 | HRH3 (0.43) | ALDH1A3APPNPC1RAB9AALDH1A1 | |
| SCHEMBL1727498 | 0.83 | HRH3 (0.56) | APPNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL1726212 | 0.83 | HRH3 (0.56) | ALDH1A3NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL1727327 | 0.82 | HRH3 (0.57) | ALDH1A3NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL3885936 | 0.81 | CYP3A4 (0.44) | ALDH1A3APPNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216994-A1 | USE OF NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID, AND PROCESS FOR PRODUCTION OF THE SAME | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2010-08-26 | — | — | US | disclosed |
| EP-2216052-A1 | USE OF NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID, AND PROCESS FOR PRODUCTION OF THE SAME | Nihon Medi-Physics Co., Ltd. (JP) | 2010-08-11 | — | — | EP | disclosed |
| US-20090252680-A1 | NOVEL COMPOUND WITH AFFINITY FOR AMYLOID | NIHON- MEDI-PHYSICS CO., LTD (JP) | 2009-10-08 | — | — | US | disclosed |
| EP-2098523-A1 | NOVEL COMPOUNDS WITH AFFINITY FOR AMYLOID | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2009-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216994-A1 | USE OF NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID, AND PROCESS FOR PRODUCTION OF THE SAME | APBA1, APP, S100A4 | ALDH1A3 2637/4885APP 2/4885NPC1 792/4885 |
| US-20090252680-A1 | NOVEL COMPOUND WITH AFFINITY FOR AMYLOID | APBA1, APP, SLC7A1 | ALDH1A3 3051/4885APP 2/4885NPC1 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.