Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 0.43 |
| ▸ | LCK | P06239 | 3/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29044464 | 0.86 | LMNA (0.62) | LMNAALDH1A1MAPK10RXFP1NPC1 | |
| SCHEMBL29044453 | 0.85 | LMNA (0.57) | LMNAALDH1A1MAPK10RXFP1NPC1 | |
| SCHEMBL29044460 | 0.79 | LMNA (0.57) | LMNAALDH1A1MAPK10RXFP1NPC1 | |
| SCHEMBL29044477 | 0.78 | PIK3CG (0.47) | LMNAALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL30522192 | 0.78 | PIK3CG (0.47) | LMNAALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL29044438 | 0.76 | ALDH1A1 (0.54) | LMNAALDH1A1MAPK10RXFP1NPC1 | |
| SCHEMBL8738378 | 0.75 | ALDH1A1 (0.97) | LMNAALDH1A1MAPK10RXFP1NPC1 | |
| Hydrochloric Acid SCHEMBL6114205 | 0.74 | ALDH1A1 (0.95) | LMNAALDH1A1MAPK10RXFP1NPC1 | |
| Bromide SCHEMBL6121128 | 0.74 | ALDH1A1 (1.00) | LMNAALDH1A1MAPK10RXFP1NPC1 | |
| SCHEMBL8737987 | 0.73 | ALDH1A1 (0.71) | LMNAALDH1A1MAPK10RXFP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116531373-B | Thiazole compound, pharmaceutical composition and application thereof | 上海日馨医药科技股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-116531373-A | Thiazole compound, pharmaceutical composition and application thereof | 上海日馨医药科技股份有限公司 | 2023-08-04 | — | — | CN | disclosed |