Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 10/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 10/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30522192 | 1.00 | PIK3CG (0.47) | PIK3CGCDK5CDK5R1PIK3CAHPGD | |
| SCHEMBL29044481 | 0.87 | PTGDR2 (0.53) | PIK3CGCDK5CDK5R1PIK3CAHPGD | |
| SCHEMBL30522187 | 0.87 | PTGDR2 (0.53) | PIK3CGCDK5CDK5R1PIK3CAHPGD | |
| SCHEMBL29044465 | 0.85 | MAPT (0.50) | PIK3CGCDK5CDK5R1PIK3CAHPGD | |
| SCHEMBL29044470 | 0.79 | MAPT (0.47) | PIK3CGCDK5CDK5R1PIK3CAHPGD | |
| SCHEMBL29044441 | 0.78 | LMNA (0.58) | CDK5CDK5R1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL11395592 | 0.77 | CYP1A2 (0.56) | HPGDMAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL29044449 | 0.77 | MAPT (0.47) | PIK3CGCDK5CDK5R1PIK3CAHPGD | |
| SCHEMBL30522185 | 0.77 | MAPT (0.47) | PIK3CGCDK5CDK5R1PIK3CAHPGD | |
| SCHEMBL8738341 | 0.75 | RAB9A (0.66) | PIK3CGCDK5CDK5R1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116531373-A | Thiazole compound, pharmaceutical composition and application thereof | 上海日馨医药科技股份有限公司 | 2023-08-04 | — | — | CN | disclosed |