Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30522185 | 1.00 | MAPT (0.47) | MAPTSMN1; SMN2KDM4EHPGDCASP1 | |
| SCHEMBL29044470 | 0.87 | MAPT (0.47) | MAPTSMN1; SMN2KDM4EHPGDCASP1 | |
| SCHEMBL29044461 | 0.85 | GAA (0.59) | MAPTSMN1; SMN2KDM4EHPGDTRPV4 | |
| SCHEMBL29044443 | 0.83 | ALDH1A1 (0.43) | MAPTSMN1; SMN2KDM4EHPGDTRPV4 | |
| SCHEMBL30522187 | 0.80 | PTGDR2 (0.53) | MAPTSMN1; SMN2KDM4EHPGDPIK3CG | |
| SCHEMBL29044481 | 0.80 | PTGDR2 (0.53) | MAPTSMN1; SMN2KDM4EHPGDPIK3CG | |
| SCHEMBL29044477 | 0.77 | PIK3CG (0.47) | MAPTSMN1; SMN2KDM4EHPGDCASP1 | |
| SCHEMBL30522192 | 0.77 | PIK3CG (0.47) | MAPTSMN1; SMN2KDM4EHPGDCASP1 | |
| SCHEMBL29044465 | 0.76 | MAPT (0.50) | MAPTSMN1; SMN2KDM4EHPGDCASP1 | |
| SCHEMBL29044438 | 0.75 | ALDH1A1 (0.54) | MAPTSMN1; SMN2KDM4ETRPV4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116531373-A | Thiazole compound, pharmaceutical composition and application thereof | 上海日馨医药科技股份有限公司 | 2023-08-04 | — | — | CN | disclosed |