Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.40 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14130437 | 0.98 | ALDH1A1 (0.48) | ALDH1A1HPGDLMNAL3MBTL1HTT | |
| Hydrochloric Acid SCHEMBL27524153 | 0.97 | ALDH1A1 (0.47) | ALDH1A1HPGDLMNAL3MBTL1HTT | |
| Bicarbonate SCHEMBL28038338 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LMNAL3MBTL1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28053725 | 0.83 | ALDH1A1 (0.39) | ALDH1A1HPGDLMNAL3MBTL1HTT | |
| Bromide SCHEMBL231675 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HPGDL3MBTL1HTTSMN1; SMN2 | |
| Bromide SCHEMBL152743 | 0.82 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1HTTSMN1; SMN2ACHE | |
| Bromide SCHEMBL2113979 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HPGDLMNAL3MBTL1HTT | |
| Bicarbonate SCHEMBL8962371 | 0.81 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1HTTSMN1; SMN2ACHE | |
| Acetic Acid SCHEMBL5720121 | 0.81 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1HTTSMN1; SMN2ACHE | |
| Bicarbonate SCHEMBL28038336 | 0.81 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1HTTSMN1; SMN2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116119974-B | Polycarboxylate superplasticizer applicable to plateau areas and preparation method thereof | 石家庄市长安育才建材有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-116119974-A | Polycarboxylate superplasticizer applicable to plateau areas and preparation method thereof | 石家庄市长安育才建材有限公司 | 2023-05-16 | — | — | CN | claimed |
| CN-116119974-B | Polycarboxylate superplasticizer applicable to plateau areas and preparation method thereof | 石家庄市长安育才建材有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116119974-A | Polycarboxylate superplasticizer applicable to plateau areas and preparation method thereof | 石家庄市长安育才建材有限公司 | 2023-05-16 | — | — | CN | disclosed |