Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF3 | O95398 | 6/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25462131 | 0.98 | RAPGEF3 (0.89) | RAPGEF3KMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL25186261 | 0.92 | RAPGEF3 (0.80) | RAPGEF3KMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL25463585 | 0.92 | RAPGEF3 (0.77) | RAPGEF3KMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL30439576 | 0.90 | RAPGEF3 (0.80) | RAPGEF3KMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL23843612 | 0.90 | RAPGEF3 (0.80) | RAPGEF3KMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL25182638 | 0.90 | RAPGEF3 (0.80) | RAPGEF3KMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL25463592 | 0.86 | RAPGEF3 (0.68) | RAPGEF3KMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL25179969 | 0.85 | RAPGEF3 (0.72) | RAPGEF3KMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL25462255 | 0.84 | RAPGEF3 (0.81) | RAPGEF3KMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL25463008 | 0.83 | RAPGEF3 (0.70) | RAPGEF3KMT2APOLBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150929-A1 | SELECTIVE NON-CYCLIC NUCLEOTIDE ACTIVATORS FOR THE CAMP SENSOR EPAC1 | UNIV TEXAS (US) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150929-A1 | SELECTIVE NON-CYCLIC NUCLEOTIDE ACTIVATORS FOR THE CAMP SENSOR EPAC1 | CREB1, RAPGEF4, ATF4 | RAPGEF3 4/4885KMT2A 4380/4885POLB 3854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.