SCHEMBL29045202

SCHEMBL29045202

CCCn1c2ccccc2c2cccc(NNC)c21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.44
LMNA P02545 3/20 0.44
MAPT P10636 2/20 0.44
TSHR P16473 2/20 0.44
MAPK1 P28482 2/20 0.44
USP2 O75604 1/20 0.44
ALOX15 P16050 1/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
PGR P06401 2/20 0.43
RORA P35398 1/20 0.43
RORC P51449 1/20 0.43
RORB Q92753 1/20 0.43
ALDH1A1 P00352 4/20 0.42
HPGD P15428 3/20 0.42
KDM4E B2RXH2 2/20 0.42
HSD17B10 Q99714 1/20 0.42
NPY5R Q15761 1/20 0.41
MEN1 O00255 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29045210 0.92 PGR (0.55) LMNATDP1PGRRORARORC
SCHEMBL28233487 0.78 CNR2 (0.48) POLBLMNAMAPTTSHRMAPK1
SCHEMBL20363636 0.76 ALKBH5 (0.61) POLBLMNAMAPTTSHRMAPK1
SCHEMBL30854944 0.75 ALDH1A1 (0.62) POLBLMNAMAPTTSHRMAPK1
SCHEMBL30012682 0.75 ALDH1A1 (0.62) POLBLMNAMAPTTSHRMAPK1
SCHEMBL153959 0.75 ALDH1A1 (0.62) POLBLMNAMAPTTSHRMAPK1
SCHEMBL28767719 0.74 ALDH1A1 (0.48) POLBLMNAMAPTTSHRMAPK1
SCHEMBL29101964 0.73 ALDH1A1 (0.60) POLBLMNAMAPTTSHRMAPK1
SCHEMBL15820194 0.73 CNR2 (0.47) POLBLMNAMAPTTSHRMAPK1
SCHEMBL6280030 0.73 KDM4E (0.50) POLBLMNAMAPTTSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116478082-A Synthesis method of carbazolyl-containing Schiff base in eutectic solvent 陕西科技大学 2023-07-25 CN disclosed