Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28411151 | 0.84 | LMNA (0.38) | HPSELMNAPDE4BPDE4D | |
| SCHEMBL28416472 | 0.81 | LMNA (0.45) | HPSELMNAPDE4BPDE4D | |
| SCHEMBL25601807 | 0.81 | LMNA (0.42) | HPSELMNAPDE4BPDE4D | |
| SCHEMBL28415816 | 0.79 | HPSE (0.35) | HPSELMNA | |
| SCHEMBL30554017 | 0.77 | ADORA2B (0.41) | LMNAOGFRL1 | |
| SCHEMBL4342320 | 0.67 | — | — | |
| SCHEMBL8611205 | 0.67 | LMNA (0.42) | LMNAPDE4BPDE4D | |
| SCHEMBL31132654 | 0.66 | KDM4E (0.33) | TGFBR1 | |
| SCHEMBL2364931 | 0.66 | LMNA (0.41) | LMNATGFBR1PDE4BPDE4D | |
| SCHEMBL27510365 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187218-B | Application of 1-substituted-1H-imidazole-2-carboxylic acid compound in preparation of metal beta-lactamase inhibitor | 四川大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-111253317-B | 1-substituted-1H-imidazole-2-carboxylic acid compound | 四川大学 | 2023-08-04 | — | — | CN | disclosed |