SCHEMBL2904570

SCHEMBL2904570

Oc1ccc(-c2ccc(OCc3cccc(COc4ccc(-c5ccc(O)cc5)cc4)c3)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.66
CYP1A2 P05177 1/20 0.66
PTGS1 P23219 1/20 0.66
SLC6A2 P23975 1/20 0.66
CYP2C19 P33261 1/20 0.66
PTGS2 P35354 1/20 0.66
SLC6A3 Q01959 1/20 0.66
HIF1A Q16665 1/20 0.66
HDAC6 Q9UBN7 1/20 0.66
F2 P00734 3/20 0.57
PTPRC P08575 1/20 0.56
PTPN1 P18031 1/20 0.56
MCL1 Q07820 1/20 0.53
APP P05067 1/20 0.52
FFAR1 O14842 4/20 0.51
AKR1B1 P15121 1/20 0.51
FFAR4 Q5NUL3 1/20 0.51
GSTP1 P09211 1/20 0.50
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5633862 0.94 LMNA (0.73) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL27458843 0.87 LMNA (0.63) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL254671 0.86 LMNA (0.88) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL18625351 0.86 LMNA (0.73) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL3918360 0.85 LMNA (0.61) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL6059234 0.85 LMNA (0.85) LMNACYP1A2PTGS1SLC6A2CYP2C19
Monobenzone SCHEMBL7269913 0.84 LMNA (0.76) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL22596639 0.84 APP (0.70) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL5633288 0.84 APP (0.70) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL22151428 0.82 LMNA (0.58) LMNACYP1A2PTGS1SLC6A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1636209-B1 EPOXY COMPOUND AND CURED EPOXY RESIN PRODUCT SUMITOMO CHEMICAL CO (JP) 2010-08-11 EP disclosed
US-7279574-B2 Epoxy compound and cured epoxy resin product SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-09 US disclosed
US-20060159929-A1 Epoxy compound and cured epoxy resin product HITACHI, LTD. (JP) 2006-07-20 US disclosed
EP-1636209-A1 EPOXY COMPOUND AND CURED EPOXY RESIN PRODUCT Sumitomo Chemical Company, Limited (JP) 2006-03-22 EP disclosed
WO-2004113327-A1 EPOXY COMPOUND AND CURED EPOXY RESIN PRODUCT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-29 WO disclosed