SCHEMBL5633862

SCHEMBL5633862

Oc1ccc(OCc2cccc(COc3ccc(O)cc3)c2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.73
CYP1A2 P05177 1/20 0.73
PTGS1 P23219 1/20 0.73
SLC6A2 P23975 1/20 0.73
CYP2C19 P33261 1/20 0.73
PTGS2 P35354 1/20 0.73
SLC6A3 Q01959 1/20 0.73
HIF1A Q16665 1/20 0.73
HDAC6 Q9UBN7 1/20 0.73
F2 P00734 3/20 0.62
PTPRC P08575 1/20 0.61
PTPN1 P18031 1/20 0.61
APP P05067 1/20 0.57
MAOB P27338 7/20 0.53
MEN1 O00255 1/20 0.53
TP53 P04637 1/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
BLM P54132 1/20 0.53
KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2904570 0.94 LMNA (0.66) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL27458843 0.92 LMNA (0.63) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL3918360 0.91 LMNA (0.61) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL22151428 0.88 LMNA (0.58) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL10866245 0.87 MAOB (0.69) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL17554431 0.87 LMNA (0.61) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL3625818 0.87 MAOB (0.73) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL3624161 0.87 MAOB (0.73) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL51406 0.86 LMNA (0.56) LMNACYP1A2PTGS1SLC6A2CYP2C19
Monobenzone SCHEMBL11272996 0.84 LMNA (1.00) LMNACYP1A2PTGS1SLC6A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0179476-A1 Polymerization inhibitors and polymerization-inhibited solutions of monomers Barnes-Hind, Inc. (US) 1986-04-30 EP claimed
US-7279574-B2 Epoxy compound and cured epoxy resin product SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-09 US disclosed
US-20060159929-A1 Epoxy compound and cured epoxy resin product HITACHI, LTD. (JP) 2006-07-20 US disclosed
EP-1636209-A1 EPOXY COMPOUND AND CURED EPOXY RESIN PRODUCT Sumitomo Chemical Company, Limited (JP) 2006-03-22 EP disclosed
WO-2004113327-A1 EPOXY COMPOUND AND CURED EPOXY RESIN PRODUCT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-29 WO disclosed