Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | LTA4H | P09960 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852321 | 0.91 | LMNA (0.64) | MAOBLTA4HRAB9ASMN1; SMN2GAA | |
| SCHEMBL11579595 | 0.89 | LTA4H (0.72) | MAOBLTA4HRAB9ASMN1; SMN2GAA | |
| SCHEMBL5677947 | 0.85 | LMNA (0.62) | MAOBLTA4HRAB9ASMN1; SMN2GAA | |
| SCHEMBL8037942 | 0.85 | TAAR1 (0.75) | LTA4HSMN1; SMN2TAAR1PLA2G2A | |
| SCHEMBL8555021 | 0.85 | TAAR1 (0.75) | LTA4HSMN1; SMN2TAAR1PLA2G2A | |
| SCHEMBL14223538 | 0.85 | TAAR1 (0.75) | LTA4HSMN1; SMN2TAAR1PLA2G2A | |
| SCHEMBL9808056 | 0.85 | LMNA (0.72) | MAOBLTA4HRAB9ASMN1; SMN2GAA | |
| SCHEMBL10795544 | 0.84 | FOXM1 (0.57) | MAOBLTA4HRAB9ASMN1; SMN2GAA | |
| SCHEMBL6505543 | 0.84 | MAOB (0.65) | MAOBLTA4HRAB9ASMN1; SMN2GAA | |
| SCHEMBL8675401 | 0.84 | LMNA (0.60) | MAOBLTA4HRAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304502-B | FOXM1 inhibitor and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-10-18 | — | — | CN | disclosed |
| CN-115304502-A | FOXM1 inhibitor and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2022-11-08 | — | — | CN | disclosed |