Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852321 | 0.94 | LMNA (0.64) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL16594362 | 0.94 | TSHR (0.56) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL903883 | 0.92 | TSHR (0.58) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL9808056 | 0.92 | LMNA (0.72) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL8675401 | 0.90 | LMNA (0.60) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL3120643 | 0.89 | TSHR (0.50) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL9478520 | 0.88 | KCNA3 (0.56) | MAOBBCHELTA4HCHRNA7TSHR | |
| SCHEMBL10795544 | 0.87 | FOXM1 (0.57) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL10713484 | 0.87 | TSHR (0.54) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL4756260 | 0.87 | MAOB (0.70) | LMNACYP1A2PTGS1SLC6A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165325-B1 | THERMALLY-RESPONSIVE RECORD MATERIAL | APPLETON PAPER INC (US) | 2006-02-08 | — | — | EP | disclosed |
| EP-1159242-A4 | MODIFIER COMPOUNDS | APPLETON PAPER INC (US) | 2004-11-24 | — | — | EP | disclosed |
| EP-1183224-B1 | PROCESS FOR PREPARING ALKOXY OR ARYLMETHOXY AROXYETHANES | APPLETON PAPER INC (US) | 2004-08-04 | — | — | EP | disclosed |
| EP-1165325-A4 | THERMALLY-RESPONSIVE RECORD MATERIAL | APPLETON PAPER INC (US) | 2004-03-24 | — | — | EP | disclosed |
| US-6566301-B2 | Heat sensitive elements | APPLETON PAPERS INC. | 2003-05-20 | — | — | US | disclosed |
| EP-1183224-A4 | PROCESS FOR PREPARING ALKOXY OR ARYLMETHOXY AROXYETHANES | APPLETON PAPER INC (US) | 2003-02-26 | — | — | EP | disclosed |
| US-6429341-B2 | MODIFIERS OF HEAT SENSITIVE RECORDING ELEMENTS COMPRISING AROMATIC ETHER DERIVATIVES E.G., 2-(BENZYLOXY)ETHYL 4-(BENZYL OXY)PHENYL ETHER; MORE INTENSE IMAGE AT LOW TEMPERATURES; HIGH SPEED RESPONSE CHROMOGENS AND ACIDIC DEVELOPERS | APPLETON PAPERS INC. | 2002-08-06 | — | — | US | disclosed |
| EP-1183224-A1 | PROCESS FOR PREPARING ALKOXY OR ARYLMETHOXY AROXYETHANES | Appleton Papers Inc. (GB) | 2002-03-06 | — | — | EP | disclosed |
| US-20020006868-A1 | Thermally-responsive record material | APPVION OPERATIONS, INC. | 2002-01-17 | — | — | US | disclosed |
| US-20020007091-A1 | Modifier compounds | APPLETON PAPERS INC. | 2002-01-17 | — | — | US | disclosed |
| US-20020002311-A1 | Process for preparing alkoxy or arylmethoxy aroxyethanes | APPLETON PAPERS INC. | 2002-01-03 | — | — | US | disclosed |
| EP-1165325-A1 | THERMALLY-RESPONSIVE RECORD MATERIAL | Appleton Papers Inc. (GB) | 2002-01-02 | — | — | EP | disclosed |
| EP-1159242-A1 | MODIFIER COMPOUNDS | Appleton Papers Inc. (GB) | 2001-12-05 | — | — | EP | disclosed |
| US-6323376-B1 | REACTING SUBSTITUTED OR UNSUBSTITUTED PHENOLS OR NAPHTHOLS WITH ETHYLENE CARBONATE IN PRESENCE OF CATALYST SELECTED FROM METAL HALIDE, QUARTERNARY AMMONIUM HALIDE AND QUARTERNARY PHOSPHONIUM HALIDE; REACTING INTERMEDIATE ARALKYL HALIDE | APPLETON PAPERS INC. | 2001-11-27 | — | — | US | disclosed |
| WO-2001060775-A1 | PROCESS FOR PREPARING ALKOXY OR ARYLMETHOXY AROXYETHANES | APPLETON PAPERS INC. (US) | 2001-08-23 | — | — | WO | disclosed |
| WO-2001049507-A1 | THERMALLY-RESPONSIVE RECORD MATERIAL | APPLETON PAPERS INC. (US) | 2001-07-12 | — | — | WO | disclosed |
| WO-2001049641-A1 | MODIFIER COMPOUNDS | APPLETON PAPERS INC. (US) | 2001-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020002311-A1 | Process for preparing alkoxy or arylmethoxy aroxyethanes | ARSA, PHYKPL, CCNY | LMNA 3418/4885CYP1A2 295/4885PTGS1 3268/4885 |
| US-20020007091-A1 | Modifier compounds | EBPL, H1-0, ADCY7 | LMNA 2643/4885CYP1A2 369/4885PTGS1 2534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.