Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 2/20 | 0.38 |
| ▸ | SETD2 | Q9BYW2 | 2/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | RPA1 | P27694 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29986915 | 1.00 | L3MBTL1 (0.41) | L3MBTL1SSTR4NSD2SETD2PARP14 | |
| SCHEMBL29045947 | 1.00 | L3MBTL1 (0.41) | L3MBTL1SSTR4NSD2SETD2PARP14 | |
| SCHEMBL29045875 | 0.86 | DYRK1A (0.41) | L3MBTL1PARP14NPC1ALOX12RAB9A | |
| SCHEMBL29045871 | 0.86 | DYRK1A (0.41) | L3MBTL1PARP14NPC1ALOX12RAB9A | |
| SCHEMBL29985509 | 0.86 | DYRK1A (0.41) | L3MBTL1PARP14NPC1ALOX12RAB9A | |
| SCHEMBL29045924 | 0.84 | PARP14 (0.38) | L3MBTL1SSTR4NSD2SETD2PARP14 | |
| SCHEMBL29045929 | 0.84 | PARP14 (0.38) | L3MBTL1SSTR4NSD2SETD2PARP14 | |
| SCHEMBL29045951 | 0.84 | PARP14 (0.54) | L3MBTL1PARP14NPC1RAB9AKDM4E | |
| SCHEMBL29045946 | 0.84 | PARP14 (0.54) | L3MBTL1PARP14NPC1RAB9AKDM4E | |
| SCHEMBL29045901 | 0.79 | BCHE (0.49) | L3MBTL1PARP14KIF11KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304597-B | Beta-carboline compounds and application thereof in preparation of medicines for treating or preventing tumor diseases | 中国科学院深圳先进技术研究院 | 2023-10-20 | — | — | CN | disclosed |
| CN-115304597-A | Beta-carboline compounds and application thereof in preparing medicines for treating or preventing tumor diseases | 中国科学院深圳先进技术研究院 | 2022-11-08 | — | — | CN | disclosed |