Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 5/20 | 0.41 |
| ▸ | CDK9 | P50750 | 4/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29045875 | 1.00 | DYRK1A (0.41) | DYRK1ACDK9DYRK1BL3MBTL1ALOX12 | |
| SCHEMBL29985509 | 1.00 | DYRK1A (0.41) | DYRK1ACDK9DYRK1BL3MBTL1ALOX12 | |
| SCHEMBL29045947 | 0.86 | L3MBTL1 (0.41) | L3MBTL1ALOX12NPC1RAB9ANCOA3 | |
| SCHEMBL29986915 | 0.86 | L3MBTL1 (0.41) | L3MBTL1ALOX12NPC1RAB9ANCOA3 | |
| SCHEMBL29045950 | 0.86 | L3MBTL1 (0.41) | L3MBTL1ALOX12NPC1RAB9ANCOA3 | |
| SCHEMBL29045951 | 0.82 | PARP14 (0.54) | DYRK1AL3MBTL1NPC1RAB9APARP14 | |
| SCHEMBL29045946 | 0.82 | PARP14 (0.54) | DYRK1AL3MBTL1NPC1RAB9APARP14 | |
| SCHEMBL29045902 | 0.80 | AR (0.42) | DYRK1AL3MBTL1PARP14PIM1PIM3 | |
| SCHEMBL29045900 | 0.80 | AR (0.42) | DYRK1AL3MBTL1PARP14PIM1PIM3 | |
| SCHEMBL29986202 | 0.80 | AR (0.42) | DYRK1AL3MBTL1PARP14PIM1PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304597-B | Beta-carboline compounds and application thereof in preparation of medicines for treating or preventing tumor diseases | 中国科学院深圳先进技术研究院 | 2023-10-20 | — | — | CN | disclosed |
| CN-115304597-A | Beta-carboline compounds and application thereof in preparing medicines for treating or preventing tumor diseases | 中国科学院深圳先进技术研究院 | 2022-11-08 | — | — | CN | disclosed |