SCHEMBL29047484

SCHEMBL29047484

O=C(O)c1c(F)cc(F)c2[nH]ccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 2/20 0.39
PTPRC P08575 1/20 0.36
PTPN2 P17706 1/20 0.36
PTPN1 P18031 1/20 0.36
PTPRB P23467 1/20 0.36
PTPRE P23469 1/20 0.36
PTPN6 P29350 1/20 0.36
KEAP1 Q14145 1/20 0.36
AURKA O14965 2/20 0.35
TPX2 Q9ULW0 2/20 0.35
IDO1 P14902 1/20 0.34
TDO2 P48775 1/20 0.34
BTK Q06187 1/20 0.34
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 3/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
ENPP2 Q13822 1/20 0.33
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15797418 0.77 P2RX7 (0.52) P2RX7KEAP1AURKATPX2IDO1
SCHEMBL21819005 0.73 PARP1 (0.40) AURKATPX2ALDH1A1KDM4EHPGD
SCHEMBL21818677 0.73 KEAP1 (0.44) P2RX7KEAP1AURKATPX2IDO1
SCHEMBL2535144 0.72 P2RX7 (0.40) P2RX7ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL5186145 0.70 PTPRC (0.45) PTPRCPTPN2PTPN1PTPRBPTPRE
SCHEMBL29047547 0.70 AURKA (0.40) AURKATPX2TDO2ALDH1A1KDM4E
SCHEMBL18203909 0.70 P2RX7 (0.41) P2RX7AURKATPX2ALDH1A1HSD17B10
SCHEMBL5187097 0.69 KEAP1 (0.49) P2RX7KEAP1AURKATPX2IDO1
SCHEMBL5188581 0.69 PTPRC (0.55) PTPRCPTPN2PTPN1PTPRBPTPRE
SCHEMBL17371702 0.69 NUDT1 (0.43) BTKKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116348477-A Functionalized peptides as antiviral agents 英安塔制药有限公司 2023-06-27 CN disclosed