Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.40 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 3/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1279155 | 0.76 | USP30 (0.61) | TDP1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL29047628 | 0.72 | HDAC1 (0.63) | KDM4EALDH1A1KMT2AMEN1AGPAT2 | |
| SCHEMBL29047581 | 0.71 | KDM4E (0.70) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL29047560 | 0.70 | KDM4E (0.67) | KDM4EALDH1A1KMT2AMEN1GLS | |
| SCHEMBL29047532 | 0.69 | KMT2A (0.70) | TDP1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL29047619 | 0.68 | SIRT2 (0.61) | KDM4EALDH1A1KMT2AMEN1GLS | |
| SCHEMBL29047642 | 0.68 | MGAM (0.51) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL5160064 | 0.68 | IDO1 (0.60) | KDM4EALDH1A1MAPTHSD17B10LMNA | |
| SCHEMBL29500525 | 0.68 | IDO1 (0.60) | KDM4EALDH1A1MAPTHSD17B10LMNA | |
| SCHEMBL6372619 | 0.67 | DDX3X (0.56) | TDP1KDM4EALDH1A1USP30GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947931-B | Thiazole amide compound, preparation method thereof, pharmaceutical composition and application | 中国科学院上海有机化学研究所 | 2023-07-07 | — | — | CN | disclosed |