Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29047560 | 0.81 | KDM4E (0.67) | ALDH1A1KDM4EHPGDNPC1HSD17B10 | |
| SCHEMBL1279155 | 0.81 | USP30 (0.61) | ALDH1A1KDM4EHPGDNPC1HSD17B10 | |
| SCHEMBL29047581 | 0.75 | KDM4E (0.70) | HDAC1HDAC2ALDH1A1KDM4EHPGD | |
| SCHEMBL29047532 | 0.73 | KMT2A (0.70) | ALDH1A1KDM4EHPGDNPC1HSD17B10 | |
| SCHEMBL29047601 | 0.72 | TDP1 (0.41) | HDAC1HDAC2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28654140 | 0.72 | ALDH1A1 (0.61) | HDAC1HDAC2ALDH1A1KDM4EHPGD | |
| SCHEMBL4089368 | 0.71 | KMT2A (0.62) | ALDH1A1KDM4EHPGDNPC1HSD17B10 | |
| SCHEMBL29047597 | 0.71 | SMN1; SMN2 (0.67) | HDAC1HDAC2ALDH1A1KDM4EHPGD | |
| SCHEMBL6372619 | 0.71 | DDX3X (0.56) | HDAC1HDAC2ALDH1A1KDM4EHPGD | |
| SCHEMBL29047587 | 0.71 | L3MBTL1 (0.60) | ALDH1A1KDM4ESMN1; SMN2TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947931-B | Thiazole amide compound, preparation method thereof, pharmaceutical composition and application | 中国科学院上海有机化学研究所 | 2023-07-07 | — | — | CN | disclosed |