Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.43 |
| ▸ | CRACR2A | Q9BSW2 | 4/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30546976 | 1.00 | LMNA (0.49) | LMNAMAPTRAB9ARXFP1CRACR2A | |
| SCHEMBL29047696 | 0.91 | LMNA (0.46) | LMNAMAPTRAB9ARXFP1CRACR2A | |
| SCHEMBL30546943 | 0.91 | LMNA (0.46) | LMNAMAPTRAB9ARXFP1CRACR2A | |
| SCHEMBL30546930 | 0.91 | LMNA (0.47) | LMNAMAPTRXFP1CRACR2A | |
| SCHEMBL29047677 | 0.91 | LMNA (0.47) | LMNAMAPTRXFP1CRACR2A | |
| SCHEMBL29047705 | 0.91 | LMNA (0.45) | LMNAMAPTRAB9ARXFP1CRACR2A | |
| SCHEMBL30546975 | 0.91 | LMNA (0.45) | LMNAMAPTRAB9ARXFP1CRACR2A | |
| SCHEMBL29047646 | 0.90 | RAB9A (0.47) | LMNAMAPTRAB9ACRACR2AMAPK13 | |
| SCHEMBL30546929 | 0.89 | RECQL (0.48) | LMNAMAPTRXFP1RECQLTAS2R14 | |
| SCHEMBL28397911 | 0.88 | KMT2A (0.52) | LMNACRACR2AKMT2ARECQLGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535357-A | Arylamino benzamide derivative containing substituted pyrazole structure, preparation method and application | 西北农林科技大学 | 2023-08-04 | — | — | CN | disclosed |