Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30546924 | 1.00 | RAB9A (0.47) | RAB9ANPC1HPGDSMN1; SMN2NUDT1 | |
| SCHEMBL29047697 | 0.90 | MAPT (0.44) | RAB9ANPC1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL30546926 | 0.90 | MAPT (0.44) | RAB9ANPC1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL30546930 | 0.90 | LMNA (0.47) | HPGDKDM4ELMNACRACR2AMAPT | |
| SCHEMBL29047677 | 0.90 | LMNA (0.47) | HPGDKDM4ELMNACRACR2AMAPT | |
| SCHEMBL29047686 | 0.90 | LMNA (0.49) | RAB9AKMT2ALMNACRACR2AMAPK14 | |
| SCHEMBL30546976 | 0.90 | LMNA (0.49) | RAB9AKMT2ALMNACRACR2AMAPK14 | |
| SCHEMBL29047640 | 0.89 | TAS2R14 (0.47) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL30546938 | 0.89 | TAS2R14 (0.47) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL30546984 | 0.87 | MAPT (0.50) | SMN1; SMN2MEN1KMT2ALMNACRACR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535357-A | Arylamino benzamide derivative containing substituted pyrazole structure, preparation method and application | 西北农林科技大学 | 2023-08-04 | — | — | CN | disclosed |