Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.30 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2805382 | 0.82 | HTR6 (0.30) | — | |
| Hydrochloric Acid SCHEMBL649398 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL6553419 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL6406861 | 0.71 | PTPRC (0.32) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL6402643 | 0.70 | PTPN1 (0.37) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL6407031 | 0.70 | PTPN1 (0.37) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL6409053 | 0.70 | PTPN1 (0.37) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL6402583 | 0.70 | PTPN1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL6404337 | 0.70 | PTPN1 (0.37) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL6400125 | 0.68 | CYP11B2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0872506-B1 | Cycloolefin copolymers and uses thereof | MITSUI CHEMICALS INC (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6063886-A | MADE FROM AN ALPHA-OLEFIN, CYCLOOLEFIN OF GIVEN FORMULAS, AND VINYL AROMATIC IN GIVEN RELATION; MOLDED ARTICLES SUCH AS FOR OPTICS HAVING HEAT RESISTANCE, TRANSPARENCY, SMALL BIREFRINGENCE | MITSUI CHEMICALS (JP) | 2000-05-16 | — | — | US | disclosed |
| EP-0872506-A1 | Cycloolefin copolymers and uses thereof | Mitsui Chemicals, Inc. (JP) | 1998-10-21 | — | — | EP | disclosed |