SCHEMBL2904812

SCHEMBL2904812

C=Cc1ccc(N2CCOCC2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.54
MAPT P10636 11/20 0.54
MEN1 O00255 6/20 0.54
KMT2A Q03164 6/20 0.54
KDM4E B2RXH2 6/20 0.54
NPC1 O15118 5/20 0.54
RAB9A P51151 5/20 0.54
SMN1; SMN2 Q16637 5/20 0.54
MITF O75030 1/20 0.53
LMNA P02545 3/20 0.52
HTT P42858 3/20 0.52
CYP1A2 P05177 1/20 0.52
HSD17B10 Q99714 4/20 0.51
HPGD P15428 4/20 0.51
TP53 P04637 2/20 0.51
ALOX15 P16050 2/20 0.50
USP2 O75604 1/20 0.50
MAPK1 P28482 1/20 0.50
GAA P10253 1/20 0.49
ALOX12 P18054 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL628551 0.89 ALDH1A1 (0.58) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL9915631 0.83 MAPT (0.73) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL98716 0.83 TRIM24 (0.63) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL9093746 0.82 LMNA (0.71) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL609198 0.81 ALDH1A1 (0.64) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL817331 0.81 ALDH1A1 (0.64) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL2904811 0.81 ALDH1A1 (0.56) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL4769361 0.80 LMNA (0.53) ALDH1A1MAPTMEN1KMT2ANPC1
SCHEMBL211336 0.79 TRIM24 (0.70) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL4419960 0.79 ALDH1A1 (0.59) ALDH1A1MAPTMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504437-A Method for denitrification alkylation of aromatic methylamine 中国科学技术大学 2025-02-25 CN claimed
CN-114436961-B Acid response fluorescent small molecule, preparation method and application thereof 吴江市汉塔纺织整理有限公司 2023-09-15 CN claimed
CN-116370645-A Endoplasmic reticulum targeted fluorescent nano-carrier, preparation method and application thereof 齐鲁工业大学(山东省科学院) 2023-07-04 CN claimed
CN-112675919-B Application of N-heterocyclic carbene-based mixed nickel (II) complex in synthesis of alpha-benzyl benzofuran compound 苏州大学 2023-06-13 CN claimed
CN-114478351-B Method for synthesizing alpha-alkyl substituted indole-3-formaldehyde compound 苏州大学 2023-04-28 CN claimed
CN-115745898-A Aromatic acrylamide-triazole compound, and preparation method and application thereof 许昌学院 2023-03-07 CN claimed
CN-114478351-A Method for synthesizing alpha-alkyl substituted indole-3-formaldehyde compound 苏州大学 2022-05-13 CN claimed
CN-114436961-A Acid-responsive fluorescent small molecule, preparation method and application thereof 吴江市汉塔纺织整理有限公司 2022-05-06 CN claimed
CN-112675919-A Application of N-heterocyclic carbene-based mixed nickel (II) complex in synthesis of alpha-benzylbenzofuran compounds 苏州大学 2021-04-20 CN claimed
EP-4539840-A1 KINASE MODULATORS AND METHODS OF USE THEREOF Neuron23, Inc. (US) 2025-04-23 EP disclosed
CN-119730846-A Kinase modulators and methods of use thereof 神经元23公司 2025-03-28 CN disclosed
CN-119504437-A Method for denitrification alkylation of aromatic methylamine 中国科学技术大学 2025-02-25 CN disclosed
CN-112645909-B Method for synthesizing alpha-benzyl benzofuran compound 苏州大学 2024-09-27 CN disclosed
WO-2023244788-A9 KINASE MODULATORS AND METHODS OF USE THEREOF NEURON23, INC. (US) 2024-09-12 WO disclosed
EP-1116723-A1 CHROMENE COMPOUNDS TOKUYAMA CORPORATION (JP) 2001-07-18 EP disclosed
EP-1054010-A1 Chromene compound TOKUYAMA CORPORATION (JP) 2000-11-22 EP disclosed
EP-1020445-A1 FUSED PYRIDINE DERIVATIVES Eisai Co., Ltd. (JP) 2000-07-19 EP disclosed
WO-2000037464-A2 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS BASILEA PHARMACEUTICA AG (CH) 2000-06-29 WO disclosed
US-5147750-A Amino group containing polymers; narrow electrostatic charge distribution SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-15 US disclosed
US-4770973-A READABLE BY OPTICAL DEVICES AND FIXED BY LIGHT Kanzaki Paper Manufacturing Limited (JP) 1988-09-13 US disclosed