SCHEMBL609198

SCHEMBL609198

C=Cc1ccc(N2CCCCC2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.64
KDM4E B2RXH2 2/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
TRIM24 O15164 1/20 0.61
TRIM33 Q9UPN9 1/20 0.61
MAPT P10636 7/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
RECQL P46063 2/20 0.52
ALOX15 P16050 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
NPC1 O15118 1/20 0.52
USP2 O75604 1/20 0.52
TP53 P04637 1/20 0.52
POLB P06746 1/20 0.52
GAA P10253 1/20 0.52
THRB P10828 1/20 0.52
HTT P42858 1/20 0.52
RAB9A P51151 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL817331 1.00 ALDH1A1 (0.64) ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33
SCHEMBL98716 0.98 TRIM24 (0.63) ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33
SCHEMBL628551 0.91 ALDH1A1 (0.58) ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33
Styrene SCHEMBL27781279 0.86 TSHR (0.54) ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33
SCHEMBL7718270 0.82 ALDH1A1 (0.69) ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33
SCHEMBL7718267 0.82 ALDH1A1 (0.69) ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33
SCHEMBL2904812 0.81 ALDH1A1 (0.54) ALDH1A1KDM4ESMN1; SMN2MAPTMEN1
SCHEMBL28072002 0.81 ALDH1A1 (0.46) ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33
SCHEMBL99032 0.81 ALDH1A1 (0.69) ALDH1A1KDM4ESMN1; SMN2MAPTMEN1
SCHEMBL6887590 0.81 ALDH1A1 (0.71) ALDH1A1KDM4ESMN1; SMN2TRIM24TRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3950724-B1 CONJUGATED DIENE COPOLYMER AND METHOD FOR MANUFACTURING CONJUGATED DIENE COPOLYMER ZEON CORP (JP) 2026-02-18 EP disclosed
US-12139572-B2 Conjugated diene copolymer and method for manufacturing conjugated diene copolymer ZS ELASTOMERS CO., LTD. (JP) 2024-11-12 US disclosed
EP-3604365-B1 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER SUMITOMO CHEMICAL CO (JP) 2024-04-24 EP disclosed
CN-113748134-B Conjugated diene copolymer and method for producing conjugated diene copolymer 瑞住合成橡胶株式会社 2024-03-08 CN disclosed
CN-110461893-B Conjugated diene polymer and method for producing conjugated diene polymer 住友化学株式会社 2023-10-27 CN disclosed
US-20220396583-A1 COMPOUNDS AS MODULATORS OF TLR2 SIGNALING NEUROPORE THERAPIES, INC. (US) 2022-12-15 US disclosed
US-11377513-B2 Conjugated diene polymer and method for producing conjugated diene polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-07-05 US disclosed
US-20220185919-A1 CONJUGATED DIENE COPOLYMER AND METHOD FOR MANUFACTURING CONJUGATED DIENE COPOLYMER ZS ELASTOMERS CO., LTD. (JP) 2022-06-16 US disclosed
US-11345713-B2 Compounds as modulators of TLR2 signaling NEUROPORE THERAPIES, INC. (US) 2022-05-31 US disclosed
EP-3950724-A1 CONJUGATED DIENE COPOLYMER AND METHOD FOR MANUFACTURING CONJUGATED DIENE COPOLYMER ZS Elastomers Co., Ltd. (JP) 2022-02-09 EP disclosed
EP-1655293-A2 Chromene compound Tokuyama Corporation (JP) 2006-05-10 EP disclosed
US-6723859-B2 BASE STRUCTURE IS A CHROMENE(3,2-A)FLUORENE RING CONTAINING SPIRO-FUSED RINGS; PHOTOCHROMIC LENSES; LARGE FADING RATE, LESS COLOR WHEN DETERIORATED, AND EXCELLENT LIGHT RESISTANCE IN THE PHOTOCHROMIC PROPERTIES TOKUYAMA CORPORATION (JP) 2004-04-20 US disclosed
US-20040014995-A1 Chromene compounds KAWABATA YUICHIRO (JP) 2004-01-22 US disclosed
US-20030096117-A1 Chromene compound TOKUYAMA CORPORATION (JP) 2003-05-22 US disclosed
US-6469076-B1 Chromene compounds TOKUYAMA CORPORATION (JP) 2002-10-22 US disclosed
EP-1054010-B1 Chromene compound TOKUYAMA CORP (JP) 2002-07-24 EP disclosed
EP-1184379-A1 CHROMENE COMPOUND TOKUYAMA CORPORATION (JP) 2002-03-06 EP disclosed
US-6340765-B1 PHOTOCHROMIC DYES AND DEVELOPMENT TOKUYAMA CORPORATION (JP) 2002-01-22 US disclosed
EP-1116723-A1 CHROMENE COMPOUNDS TOKUYAMA CORPORATION (JP) 2001-07-18 EP disclosed
EP-1054010-A1 Chromene compound TOKUYAMA CORPORATION (JP) 2000-11-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014995-A1 Chromene compounds SMARCE1, SMARCB1, SMARCA2 ALDH1A1 2905/4885KDM4E 985/4885SMN1; SMN2 1956/4885
US-11345713-B2 Compounds as modulators of TLR2 signaling TLR2, TLR4, TLR3 ALDH1A1 4464/4885KDM4E 4623/4885SMN1; SMN2 779/4885
US-20220396583-A1 COMPOUNDS AS MODULATORS OF TLR2 SIGNALING TLR2, TLR4, TLR3 ALDH1A1 4464/4885KDM4E 4623/4885SMN1; SMN2 779/4885
US-20030096117-A1 Chromene compound SMARCE1, SMARCD2, SMARCB1 ALDH1A1 3101/4885KDM4E 945/4885SMN1; SMN2 1950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.