Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1819167 | 0.64 | ALDH1A1 (0.54) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL628779 | 0.64 | ALDH1A1 (0.54) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL6876943 | 0.63 | ALDH1A1 (0.37) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL6876939 | 0.63 | ALDH1A1 (0.37) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL1435468 | 0.63 | FBP1 (0.58) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL1435469 | 0.63 | FBP1 (0.58) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL25819110 | 0.63 | ALDH1A1 (0.36) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL18345536 | 0.62 | ALDH1A1 (0.35) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL18921318 | 0.62 | RAF1 (0.53) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL18345851 | 0.62 | ALDH1A1 (0.35) | ALDH1A1TRPA1LMNAALOX5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547281-A | Isoxazolidines as RIPK1 inhibitors and uses thereof | 赛诺菲 | 2023-08-04 | — | — | CN | disclosed |