SCHEMBL628779

SCHEMBL628779

N#Cc1ccc(C=CC=O)cc1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
MAPT P10636 3/20 0.54
KDM4E B2RXH2 2/20 0.54
FBP1 P09467 4/20 0.53
LMNA P02545 3/20 0.52
TRPA1 O75762 1/20 0.52
ALOX5 P09917 1/20 0.52
MAPK1 P28482 1/20 0.52
HDAC2 Q92769 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.47
P4HB P07237 3/20 0.46
XDH P47989 1/20 0.44
HTT P42858 1/20 0.42
SNCA P37840 1/20 0.41
GAA P10253 1/20 0.41
NR1H3 Q13133 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1819167 1.00 ALDH1A1 (0.54) ALDH1A1MAPTKDM4EFBP1LMNA
SCHEMBL18921375 0.94 FBP1 (0.49) ALDH1A1MAPTKDM4EFBP1LMNA
SCHEMBL18921374 0.94 FBP1 (0.49) ALDH1A1MAPTKDM4EFBP1LMNA
SCHEMBL6943378 0.92 HDAC2 (0.53) ALDH1A1MAPTKDM4EFBP1LMNA
SCHEMBL6943381 0.92 HDAC2 (0.53) ALDH1A1MAPTKDM4EFBP1LMNA
SCHEMBL9971655 0.86 HDAC2 (0.58) ALDH1A1MAPTKDM4EFBP1LMNA
SCHEMBL29966035 0.83 FBP1 (0.50) ALDH1A1MAPTKDM4EFBP1LMNA
SCHEMBL8699093 0.81 FBP1 (0.59) ALDH1A1MAPTKDM4EFBP1LMNA
SCHEMBL1687898 0.81 FBP1 (0.59) ALDH1A1MAPTKDM4EFBP1LMNA
SCHEMBL21574805 0.81 FBP1 (0.59) ALDH1A1MAPTKDM4EFBP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3143055-A2 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP Bridgestone Corporation (JP) 2017-03-22 EP claimed
WO-2015175280-A2 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS CONTAINING A CYANO GROUP BRIDGESTONE CORPORATION (JP) 2015-11-19 WO claimed
EP-1963344-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2008-09-03 EP claimed
EP-1929072-A1 CORROSION INHIBITOR COMPOSITIONS AND ASSOCIATED METHODS Halliburton Energy Services, Inc. (US) 2008-06-11 EP claimed
WO-2007071453-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2007-06-28 WO claimed
WO-2007034155-A1 CORROSION INHIBITOR COMPOSITIONS AND ASSOCIATED METHODS HALLIBURTON ENERGY SERVICES, INC. (US) 2007-03-29 WO claimed
EP-1689911-A1 METHODS AND COMPOSITIONS FOR INHIBITING METAL CORROSION Halliburton Energy Services, Inc. (US) 2006-08-16 EP claimed
WO-2005054544-A1 METHODS AND COMPOSITIONS FOR INHIBITING METAL CORROSION HALLIBURTON ENERGY SERVICES, INC. (US) 2005-06-16 WO claimed
CN-118530236-A Azaindoles method for synthesizing compound 大连理工大学 2024-08-23 CN disclosed
CN-118530156-A Synthesis method of chiral beta-substituted tryptophan derivative 大连理工大学 2024-08-23 CN disclosed
US-20240247024-A1 INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE (NNMT) UNIVERSITEIT LEIDEN (NL) 2024-07-25 US disclosed
CN-118251445-A Cyclic organosiloxane containing imide bond and polymerizable unsaturated bond and curable resin composition containing the same 信越化学工业株式会社 2024-06-25 CN disclosed
EP-4314002-A1 INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE (NNMT) Universiteit Leiden (NL) 2024-02-07 EP disclosed
CN-112204076-B Resin composition, prepreg, metal foil-clad laminate, resin sheet, and printed wiring board 三菱瓦斯化学株式会社 2023-10-24 CN disclosed
US-4734461-A COUPLING AGENTS ENIRICERCHE S.P.A. (IT) 1988-03-29 US disclosed
EP-0212693-A1 Method for coupling polymers obtained by the anionic polymerization of dienic and/or vinylaromatic monomers ENIRICERCHE S.p.A. (IT) 1987-03-04 EP disclosed
EP-0201352-A2 Alkene derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-11-12 EP disclosed
EP-0073456-B1 TETRAAZAANNULENE COBALT COMPLEX COMPOUNDS AND METHOD FOR PREPARATION THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-11-27 EP disclosed
US-4033845-A [2-(4-Oxo-4H-1-benzopyran-2-yl)ethenyl]benzonitriles and benzoic acids WARNER-LAMBERT COMPANY (US) 1977-07-05 US disclosed
US-4001130-A DETERGENTS, SUBSTITUTED BUTADIENES HOECHST AKTIENGESELLSCHAFT (DT) 1977-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240247024-A1 INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE (NNMT) NNMT, NAMPT, NNT ALDH1A1 629/4885MAPT 58/4885KDM4E 1350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.