Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30339230 | 1.00 | KMT2A (0.36) | KMT2AMEN1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL25816527 | 1.00 | KMT2A (0.36) | KMT2AMEN1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL22210924 | 1.00 | KMT2A (0.36) | KMT2AMEN1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL30339025 | 1.00 | KMT2A (0.36) | KMT2AMEN1MAPTTSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30339099 | 0.89 | MEN1 (0.31) | KMT2AMEN1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL25816509 | 0.84 | GPR119 (0.46) | GPR119RECQLUSP30 | |
| SCHEMBL30547544 | 0.84 | GPR119 (0.46) | GPR119RECQLUSP30 | |
| SCHEMBL18921388 | 0.83 | RIPK1 (0.35) | ALDH1A1LMNA | |
| SCHEMBL29048222 | 0.83 | GPR119 (0.34) | TSHRGPR119RECQLGRM5ELANE | |
| SCHEMBL29048248 | 0.83 | DGAT1 (0.39) | KMT2AMEN1MAPTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547281-A | Isoxazolidines as RIPK1 inhibitors and uses thereof | 赛诺菲 | 2023-08-04 | — | — | CN | disclosed |