SCHEMBL29048447

SCHEMBL29048447

COc1cc(C(=O)OCc2ccccc2)c(-c2ccccc2)c(OC)c1OC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 1/20 0.55
PDE4D Q08499 1/20 0.55
PDE7A Q13946 1/20 0.55
PDE3A Q14432 1/20 0.55
PDE7B Q9NP56 1/20 0.55
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
POLB P06746 1/20 0.49
ALDH1A1 P00352 2/20 0.48
TDP1 Q9NUW8 3/20 0.47
PKM P14618 2/20 0.46
MAPK1 P28482 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
CYP3A4 P08684 1/20 0.45
TSHR P16473 1/20 0.45
HTT P42858 1/20 0.44
MGAM O43451 1/20 0.44
GAA P10253 1/20 0.44
SI P14410 1/20 0.44
MGAM2 Q2M2H8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21501007 0.82 TDP1 (0.52) PDE4BPDE4DPDE7APDE3APDE7B
SCHEMBL6753175 0.81 ALDH1A1 (0.52) PDE4BPDE4DPDE7APDE3APDE7B
SCHEMBL22080490 0.80 PKM (0.68) PDE4BPDE4DPDE7APDE3APDE7B
SCHEMBL13701209 0.78 HTT (0.67) PDE4BPDE4DPDE7APDE3APDE7B
SCHEMBL28171736 0.77 RAB9A (0.65) KMT2AMEN1POLBALDH1A1TDP1
SCHEMBL8432905 0.76 ALDH1A1 (0.65) KMT2AMEN1POLBALDH1A1TDP1
SCHEMBL24983872 0.76 MEN1 (0.48) PDE4BPDE4DPDE7APDE3APDE7B
SCHEMBL17736786 0.75 ALDH1A1 (0.49) KMT2AMEN1POLBALDH1A1TDP1
SCHEMBL23182775 0.75 KMT2A (0.55) KMT2AMEN1POLBALDH1A1TDP1
SCHEMBL23182973 0.75 KMT2A (0.55) KMT2AMEN1POLBALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805674-B Polymeric phosphine ligands, transition metal complexes comprising same, preparation and use thereof 中国科学院上海有机化学研究所 2023-08-11 CN disclosed