SCHEMBL29048463

SCHEMBL29048463

CC#CCCCc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.51
MAOB P27338 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
SIGMAR1 Q99720 2/20 0.45
MAOA P21397 1/20 0.45
HTR3A P46098 1/20 0.44
CHRM2 P08172 1/20 0.44
HTR1A P08908 1/20 0.44
ADRA2A P08913 1/20 0.44
CHRM1 P11229 1/20 0.44
DRD1 P21728 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
ADRA1A P35348 1/20 0.44
OPRM1 P35372 1/20 0.44
DRD3 P35462 1/20 0.44
SLC6A3 Q01959 1/20 0.44
KCNH2 Q12809 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3919310 0.86 GRM5 (0.49) GRM5MAOBMAOAKCNH2
SCHEMBL5966248 0.82 GRM5 (0.50) GRM5MAOBSIGMAR1MAOAADRA1A
SCHEMBL2093416 0.78 GRM5 (0.47) GRM5MAOBSIGMAR1MAOAADRA1A
SCHEMBL6014414 0.78 MAOA (0.50) GRM5MAOBSIGMAR1MAOAHTR3A
SCHEMBL2496079 0.78 GRM5 (0.47) GRM5MAOBSIGMAR1MAOAHTR3A
SCHEMBL28117229 0.78 GRM5 (0.47) GRM5MAOBSIGMAR1MAOAADRA1A
SCHEMBL28175144 0.78 GRM5 (0.51) GRM5MAOBSIGMAR1MAOAADRA1A
SCHEMBL29019622 0.78 GRM5 (0.47) GRM5MAOBSIGMAR1MAOAADRA1A
SCHEMBL3678249 0.78 GRM5 (0.55) GRM5L3MBTL1MEN1KMT2ASIGMAR1
SCHEMBL6014547 0.78 L3MBTL1 (0.50) GRM5L3MBTL1MEN1KMT2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114950558-B Bipiperidine skeleton tetradentate nitrogen-containing manganese catalyst and method for catalyzing hydrocarbon molecule benzyl site selective oxidation by using same 陕西师范大学 2023-08-11 CN disclosed
CN-114950558-A Bipiperidine skeleton tetradentate nitrogen-containing manganese catalyst and method for catalyzing benzyl-site selective oxidation of hydrocarbon molecules by using same 陕西师范大学 2022-08-30 CN disclosed