Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29048463 | 0.78 | GRM5 (0.51) | GRM5L3MBTL1MEN1KMT2ASIGMAR1 | |
| SCHEMBL37703522 | 0.77 | GRM5 (0.49) | GRM5SIGMAR1 | |
| SCHEMBL5966248 | 0.77 | GRM5 (0.50) | GRM5SIGMAR1MAOAADRA1ASLC6A3 | |
| SCHEMBL3219045 | 0.75 | DHFR (0.40) | GRM5SIGMAR1DRD3KCNH2 | |
| SCHEMBL19608779 | 0.75 | L3MBTL1 (0.48) | L3MBTL1 | |
| SCHEMBL5045072 | 0.74 | CALM1 (0.49) | L3MBTL1SIGMAR1AOC3 | |
| SCHEMBL29019622 | 0.74 | GRM5 (0.47) | GRM5SIGMAR1MAOAADRA1ASLC6A3 | |
| SCHEMBL6014414 | 0.74 | MAOA (0.50) | GRM5SIGMAR1MAOAADRA1ASLC6A3 | |
| SCHEMBL2496079 | 0.74 | GRM5 (0.47) | GRM5SIGMAR1MAOAADRA1ASLC6A3 | |
| SCHEMBL2093416 | 0.74 | GRM5 (0.47) | GRM5SIGMAR1MAOAADRA1ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013186550-A1 | COMPOUND AND METHOD | UNIVERSITY OF BRISTOL (GB) | 2013-12-19 | — | — | WO | disclosed |
| US-7781599-B2 | economical; nontoxic; high yield; industrial scale; Grignard reaction; iron catalyst (FeCl3) and a diamine (ethylenediamine); cross-coupling of alkyl halide and aromatic organometallic; primary or secondary alkyl substituents; phenylcycloheptane from bromocycloheptane and phenyl magnesium bromide | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-08-24 | — | — | US | disclosed |
| US-20070123734-A1 | Process for production of aromatic compounds | JAPAN SCIENCE AND TECHNOLOGY AGENCY | 2007-05-31 | — | — | US | disclosed |
| EP-1724248-A1 | PROCESS FOR PRODUCTION OF AROMATIC COMPOUNDS | Japan Science and Technology Agency (JP) | 2006-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123734-A1 | Process for production of aromatic compounds | C9, C5, C1S | GRM5 2260/4885L3MBTL1 1734/4885MEN1 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.