SCHEMBL29048468

SCHEMBL29048468

Fc1ccc(CCCCN2CCC(c3ccc(F)cc3)CC2)cc1

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.68
MEN1 O00255 1/20 0.68
TP53 P04637 1/20 0.68
CYP1A2 P05177 1/20 0.68
CYP3A4 P08684 1/20 0.68
CYP2D6 P10635 1/20 0.68
TSHR P16473 1/20 0.68
CYP2C19 P33261 1/20 0.68
KMT2A Q03164 1/20 0.68
HTR1A P08908 2/20 0.56
DRD2 P14416 2/20 0.56
HTR2A P28223 2/20 0.56
DRD3 P35462 2/20 0.56
DRD1 P21728 1/20 0.56
DRD5 P21918 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7372250 0.93 SIGMAR1 (0.81) SIGMAR1MEN1TP53CYP1A2CYP3A4
SCHEMBL8011291 0.91 DRD2 (0.65) SIGMAR1MEN1TP53CYP1A2CYP3A4
SCHEMBL8001978 0.89 DRD2 (0.63) SIGMAR1MEN1TP53CYP1A2CYP3A4
SCHEMBL8001944 0.87 DRD2 (0.65) SIGMAR1MEN1TP53CYP1A2CYP3A4
SCHEMBL8012789 0.84 DRD2 (0.60) SIGMAR1HTR1ADRD2HTR2ADRD3
SCHEMBL256669 0.83 DRD2 (0.58) SIGMAR1HTR1ADRD2HTR2ADRD3
SCHEMBL11518718 0.82 CCR3 (0.73) SIGMAR1CYP1A2CYP3A4CYP2D6HTR2A
SCHEMBL8571166 0.81 DRD2 (0.59) SIGMAR1HTR1ADRD2HTR2ADRD3
SCHEMBL6998658 0.81 DRD2 (0.59) SIGMAR1HTR1ADRD2HTR2ADRD3
SCHEMBL3595429 0.81 DRD2 (0.59) SIGMAR1MEN1TP53CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114950558-B Bipiperidine skeleton tetradentate nitrogen-containing manganese catalyst and method for catalyzing hydrocarbon molecule benzyl site selective oxidation by using same 陕西师范大学 2023-08-11 CN disclosed
CN-114950558-A Bipiperidine skeleton tetradentate nitrogen-containing manganese catalyst and method for catalyzing benzyl-site selective oxidation of hydrocarbon molecules by using same 陕西师范大学 2022-08-30 CN disclosed