Toluene

Toluene

SCHEMBL29048607

Cc1ccccc1.NCCS

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.58
LMNA P02545 2/20 0.58
ALOX12 P18054 1/20 0.58
ACHE P22303 1/20 0.58
KIF11 P52732 7/20 0.44
TAAR1 Q96RJ0 4/20 0.42
CYP2A6 P11509 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 2/20 0.42
IDO1 P14902 2/20 0.40
LOXL2 Q9Y4K0 2/20 0.40
HTR2A P28223 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
KCNH2 Q12809 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
BLM P54132 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL3861980 0.86 ACHE (0.69) TSHRLMNAALOX12ACHEKIF11
Toluene SCHEMBL2399267 0.81 LMNA (0.61) TSHRLMNAALOX12ACHEKIF11
Toluene SCHEMBL4774666 0.80 ACHE (0.69) TSHRLMNAALOX12ACHEKIF11
Toluene SCHEMBL4224679 0.80
Toluene SCHEMBL9815551 0.79 TSHR (0.58) TSHRLMNAALOX12ACHEKIF11
Toluene SCHEMBL29163622 0.79 LMNA (0.58) TSHRLMNAALOX12ACHEKIF11
Toluene SCHEMBL28417753 0.78 ACHE (0.65) TSHRLMNAALOX12ACHEKIF11
Toluene SCHEMBL2566607 0.76
Toluene SCHEMBL2508427 0.76
Benzene SCHEMBL790091 0.76 CYP3A4 (0.73) TSHRLMNATAAR1CYP2A6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116572617-A Packaging structure and method for enhancing thermal conduction between thermal interface material and soaking plate interface 长沙安牧泉智能科技有限公司 2023-08-11 CN disclosed