SCHEMBL29048671

SCHEMBL29048671

COc1ccccc1-c1cc(-c2ccc(-c3ccccc3)cc2N)ccn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.46
FEN1 P39748 1/20 0.46
MAP4K4 O95819 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA3 P34903 1/20 0.43
HSP90AA1 P07900 2/20 0.42
ALDH1A1 P00352 2/20 0.42
TP53 P04637 2/20 0.42
CYP1A2 P05177 2/20 0.42
MAPK1 P28482 2/20 0.42
CYP2C19 P33261 2/20 0.42
CLK4 Q9HAZ1 2/20 0.42
FYN P06241 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.42
HIF1A Q16665 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30525987 0.86 HSP90AA1 (0.51) ALOX5APFEN1HSP90AA1ALDH1A1TP53
SCHEMBL29048623 0.81 ENPP3 (0.48) ALDH1A1MAPK1HSD17B10GRM5MAPT
SCHEMBL29048617 0.78 PTPRC (0.41) ALOX5APFEN1ALDH1A1MAPK1HSD17B10
SCHEMBL29048645 0.77 DYRK1A (0.43) ALOX5APFEN1ALDH1A1CYP1A2MAPK1
SCHEMBL29048636 0.75 DYRK1A (0.47) ALDH1A1TP53MAPK1FYNTSHR
SCHEMBL28452211 0.75 HSP90AA1 (0.53) HSP90AA1ALDH1A1TP53CYP1A2MAPK1
SCHEMBL28916446 0.73 DYRK1A (0.54) GABRA1GABRG2GABRB3GABRA3ALDH1A1
SCHEMBL3361169 0.72 DYRK1A (0.60) ALOX5APFEN1MAP4K4HSP90AA1CYP1A2
SCHEMBL18543857 0.71 ALDH1A1 (0.48) ALOX5APFEN1ALDH1A1HSD17B10DHFR
SCHEMBL28579059 0.71 PIK3CA (0.50) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110446770-B Reversible thermochromic composition and reversible thermochromic microcapsule pigment containing the same 百乐墨水株式会社 2023-08-08 CN disclosed