SCHEMBL29048690

SCHEMBL29048690

C=CC(=O)Oc1cccc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 1/20 0.44
THRB P10828 1/20 0.42
MAPT P10636 3/20 0.41
CYP3A4 P08684 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALOX15 P16050 2/20 0.41
MAPK1 P28482 2/20 0.41
HSD17B10 Q99714 2/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
EGFR P00533 1/20 0.41
TP53 P04637 1/20 0.41
PKM P14618 1/20 0.41
HPGD P15428 1/20 0.41
ALOX12 P18054 1/20 0.41
JAK1 P23458 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NR1H2 P55055 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29048680 0.90 ADORA2A (0.49) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL29048677 0.86 PDE6D (0.51) THRBMAPTCYP3A4MEN1KMT2A
SCHEMBL30833341 0.85 EPHX1 (0.50) ALOX5
SCHEMBL16821065 0.85 EPHX1 (0.50) ALOX5
SCHEMBL379254 0.84 MEN1 (0.45) THRBMEN1KMT2AALOX5
SCHEMBL16191264 0.83 ALOX15 (0.44) THRBMAPTCYP3A4MEN1KMT2A
Acetic Acid SCHEMBL6685149 0.81 MAPT (0.48) MAPTTDP1ALOX5
SCHEMBL17991367 0.80 PIK3CA (0.36) PIK3CAMAPTCYP3A4MEN1KMT2A
SCHEMBL2124788 0.80 PLG (0.44) PIK3CATHRBMAPTCYP3A4MEN1
SCHEMBL421454 0.78 KMT2A (0.56) THRBMAPTCYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110709387-B Novel cyclic compound and organic light-emitting device using same 株式会社LG化学 2023-08-08 CN disclosed