Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE6D | O43924 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819185 | 0.88 | THRB (0.51) | PDE6DTHRBKMT2AMEN1MAPT | |
| SCHEMBL8927324 | 0.88 | THRB (0.51) | PDE6DTHRBKMT2AMEN1MAPT | |
| SCHEMBL29048690 | 0.86 | PIK3CA (0.44) | PDE6DTHRBKMT2AMEN1MAPT | |
| SCHEMBL16191264 | 0.84 | ALOX15 (0.44) | PDE6DTHRBKMT2AMEN1MAPT | |
| SCHEMBL22064860 | 0.83 | THRB (0.47) | PDE6DTHRBKMT2AMEN1MAPT | |
| SCHEMBL14130799 | 0.82 | PARP10 (0.54) | PDE6DTHRBKMT2AMEN1MAPT | |
| SCHEMBL28005885 | 0.81 | LMNA (0.50) | PDE6DTHRBKMT2AMEN1MAPT | |
| Hydrogen Sulfide SCHEMBL27808065 | 0.81 | THRB (0.46) | PDE6DTHRBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19524158 | 0.80 | ESR1 (0.49) | PDE6DTHRBKMT2AMEN1MAPT | |
| SCHEMBL802752 | 0.80 | THRB (0.58) | PDE6DTHRBKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110709387-B | Novel cyclic compound and organic light-emitting device using same | 株式会社LG化学 | 2023-08-08 | — | — | CN | disclosed |