SCHEMBL2904870

SCHEMBL2904870

COc1cccc(Nc2ccc3c(NS(=O)(=O)c4cc(F)cc(F)c4)cccc3n2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
POLB P06746 1/20 0.49
HTT P42858 2/20 0.47
TSHR P16473 1/20 0.47
ABCG2 Q9UNQ0 3/20 0.45
ABCB1 P08183 2/20 0.45
KEAP1 Q14145 2/20 0.45
NFE2L2 Q16236 2/20 0.45
PIK3CD O00329 1/20 0.45
PIK3CA P42336 1/20 0.45
PIK3CB P42338 1/20 0.45
PIK3CG P48736 1/20 0.45
MAPT P10636 4/20 0.44
MAPK1 P28482 1/20 0.44
TP53 P04637 1/20 0.44
TNNI3K Q59H18 1/20 0.44
ALPL P05186 1/20 0.44
RAF1 P04049 1/20 0.43
BRAF P15056 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2906872 0.87 SLC10A2 (0.45) MEN1KMT2AHTTABCG2ABCB1
SCHEMBL2904980 0.84 EGFR (0.44) MEN1KMT2AABCG2MAPTTP53
SCHEMBL2910554 0.83 CLK1 (0.52) MEN1KMT2APOLBABCG2MAPT
SCHEMBL2901922 0.82 MAPT (0.40) MEN1KMT2APOLBABCG2MAPT
SCHEMBL2907742 0.79 RECQL (0.53) MEN1KMT2AHTTKEAP1NFE2L2
SCHEMBL2904790 0.77 F2 (0.45) MEN1KMT2APOLBPIK3CAMAPT
SCHEMBL2905387 0.76 RECQL (0.39) MEN1KMT2AMAPTGLO1SLC40A1
SCHEMBL2905319 0.74 LMNA (0.44) MEN1KMT2APOLBHTTTSHR
SCHEMBL2906708 0.74 IDO1 (0.42) KMT2AHTTABCB1MAPTKDM4E
SCHEMBL1615576 0.74 CA1 (0.38) MEN1KMT2AMAPTPDE4BSLC40A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7825253-B2 2-aminoquinoline derivatives HOFFMANN-LA ROCHE INC. (US) 2010-11-02 US claimed
EP-2076495-B1 QUINOLINE DERIVATIVES WITH 5-HT-BINDING PROPERTIES HOFFMANN LA ROCHE (CH) 2010-08-18 EP claimed
EP-2076495-A1 QUINOLINE DERIVATIVES WITH 5-HT-BINDING PROPERTIES F.HOFFMANN-LA ROCHE AG (CH) 2009-07-08 EP claimed
WO-2008037626-A1 QUINOLINE DERIVATIVES WITH 5-HT-BINDING PROPERTIES F. HOFFMANN-LA ROCHE AG (CH) 2008-04-03 WO claimed
US-20080081907-A1 2-AMINOQUINOLINE DERIVATIVES HOFFMANN-LA ROCHE INC. 2008-04-03 US claimed
EP-4695321-A1 VINYL ACETATE HAVING LOW DEUTERIUM CONTENT BASF SE (DE) 2026-02-18 EP disclosed
EP-4688728-A1 PROCESS FOR THE PREPARATION OF AMINO ACID ESTERS AS ORGANOETHER SULFATE SALTS FROM ALKOXYLATED ALCOHOLS BASF SE (DE) 2026-02-11 EP disclosed
WO-2025238047-A1 CELLULOSE ACETATE WITH LOW DEGREE OF SUBSTITUTION BASF SE (DE) 2025-11-20 WO disclosed
WO-2025223955-A1 METHOD FOR PRODUCING POLYASPARTIC ACID, POLYASPARTIC ACID AND ITS USE BASF SE (DE) 2025-10-30 WO disclosed
US-20250297192-A1 BIODEGRADABLE GRAFT POLYMERS USEFUL FOR DYE TRANSFER INHIBITION BASF SE (DE) 2025-09-25 US disclosed
EP-4605514-A1 ODOR CONTROLLING BACTERIA BASF SE (DE) 2025-08-27 EP disclosed
EP-4558536-A1 BIODEGRADABLE GRAFT POLYMERS USEFUL FOR DYE TRANSFER INHIBITION BASF SE (DE) 2025-05-28 EP disclosed
WO-2008037626-A1 QUINOLINE DERIVATIVES WITH 5-HT-BINDING PROPERTIES F. HOFFMANN-LA ROCHE AG (CH) 2008-04-03 WO disclosed
US-20080081907-A1 2-AMINOQUINOLINE DERIVATIVES HOFFMANN-LA ROCHE INC. 2008-04-03 US disclosed
US-20060105418-A1 Immobilization support, process for producing the same, electrode, process for producing the same, electrode reaction utilizing apparatus and process for producing the same MURATA MANUFACTURING CO., LTD. (JP) 2006-05-18 US disclosed
EP-1630227-A1 IMMOBILIZATION SUPPORT, PROCESS FOR PRODUCING THE SAME, ELECTRODE, PROCESS FOR PRODUCING THE SAME, ELECTRODE REACTION UTILIZING APPARATUS AND PROCESS FOR PRODUCING THE SAME Sony Corporation (JP) 2006-03-01 EP disclosed
US-20030135172-A1 Absorbent article BASF AKTIENGESELLSCHAFT (DE) 2003-07-17 US disclosed
EP-0085166-B1 A FILTER AND A PROCESS FOR THE PREPARATION THEREOF New York Blood Center, Inc. (US) 1986-06-25 EP disclosed
US-4460686-A Glucose oxidation with immobilized glucose oxidase-catalase BOEHRINGER INGELHEIM GMBH (DE) 1984-07-17 US disclosed
US-4397949-A Preparation and immobilization of inulinase STAMICARBON, B.V. (NL) 1983-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080081907-A1 2-AMINOQUINOLINE DERIVATIVES AR, ADRA2C, RCC2 MEN1 645/4885KMT2A 335/4885POLB 3619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.