SCHEMBL29048726

SCHEMBL29048726

Cc1ccc(S(=O)(=O)Nc2ccc(C)cc2C)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.77
MEN1 O00255 2/20 0.66
KMT2A Q03164 2/20 0.66
HTT P42858 2/20 0.66
MAPT P10636 1/20 0.66
MAPK1 P28482 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
ALDH1A1 P00352 3/20 0.66
GAA P10253 2/20 0.66
GFER P55789 1/20 0.66
KEAP1 Q14145 1/20 0.64
NFE2L2 Q16236 1/20 0.64
TP53 P04637 1/20 0.63
CA1 P00915 1/20 0.63
CA2 P00918 1/20 0.63
CA4 P22748 1/20 0.63
CA7 P43166 1/20 0.63
CA9 Q16790 1/20 0.63
NPC1 O15118 1/20 0.62
LMNA P02545 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12903521 0.90 FFAR4 (0.68) FFAR4MEN1KMT2AHTTMAPT
SCHEMBL578654 0.89 FFAR4 (0.68) FFAR4MEN1KMT2AHTTMAPT
SCHEMBL15248886 0.87 HSD17B2 (0.74) FFAR4MEN1KMT2AHTTMAPT
SCHEMBL7580401 0.87 CA1 (0.70) FFAR4MAPTALDH1A1GAAGFER
SCHEMBL3379842 0.86 FFAR4 (0.60) FFAR4MEN1KMT2AHTTMAPT
SCHEMBL7178299 0.86 CYTH2 (0.73) FFAR4MEN1KMT2AHTTMAPT
SCHEMBL16325550 0.86 FFAR4 (0.63) FFAR4MEN1KMT2AHTTMAPT
SCHEMBL13852837 0.85 HSD17B2 (0.68) FFAR4HTTMAPTALDH1A1GAA
SCHEMBL7595414 0.85 ALDH1A1 (0.70) FFAR4HTTMAPTALDH1A1GAA
SCHEMBL13852947 0.84 NPC1 (0.58) FFAR4MEN1KMT2AHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116574039-B Polysubstituted aminobenzonitrile compound and preparation method thereof 上海大学 2025-02-28 CN disclosed
CN-116574039-A Polysubstituted aminobenzonitrile compound and preparation method thereof 上海大学 2023-08-11 CN disclosed